E-TABM-916 - Transcription profiling of Bos taurus 4 brain areas at either of 2 phases of oestrous cycle
Released on 3 February 2011, last updated on 2 May 2014
The experiment is part of a study aimed at identifying and studying genes that contribute to differences in oestrous behaviour expression and fertility levels of dairy cows. Samples from 4 brain areas (dorsal hypothalamus, ventral hypothalamus, amygdala and hippocampus) and the anterior pituitary were collected from 28 primiparous Holstein Friesian cows, 14 of which were sacrificed at start of oestrus and 14 at mid of oestrous cycle. Differential gene expression between the 2 phases of oestrous cycle as well as the association of gene expression patterns with the level of oestrous behaviour expression are studied.
transcription profiling by array, co-expression, dye swap, innate behavior, organism part comparison, reference, replicate
Regional regulation of transcription in the bovine genome. Kommadath A, Nie H, Groenen MA, te Pas MF, Veerkamp RF, Smits MA. :e20413 (2011), PMID:21673989
Gene expression patterns in four brain areas associate with quantitative measure of estrous behavior in dairy cows. Kommadath A, Woelders H, Beerda B, Mulder HA, de Wit AA, Veerkamp RF, te Pas MF, Smits MA. :200 (2011), PMID:21504592
Prioritization of candidate genes for cattle reproductive traits, based on protein-protein interactions, gene expression, and text-mining. Ina Hulsegge; Henri Woelders; Mari Smits; Dirkjan Schokker; Li Jiang; Peter Sorensen. Physiol Genomics 45(10):400 (2013), PMID:23572538