E-TABM-1140 - Transcription profiling by array of subcutaneous fat, skin and LCLs dervied from 856 TwinsUK participants
Released on 1 June 2011, last updated on 2 May 2014
Sequence-based variation in gene expression is a key driver of disease risk. Common variants regulating expression in cis have been mapped in many eQTL studies typically in single tissues from unrelated individuals. Here, we present a comprehensive analysis of gene expression across multiple tissues conducted in a large set of female individuals that allows systematic dissection of genetic and non-genetic effects on gene expression. Gene expression was quantified in subcutaneous fat, skin and LCLs derived from 856 TwinsUK participants using Illumina whole genome expression array (HumanHT-12 version 3). Microarray methylation data from the same cohort has also been deposited at ArrayExpress under accession E-MTAB-1866 (https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-1866/).
transcription profiling by array, organism part comparison
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