E-MTAB-6701 - Reconstructing the human first trimester fetal-maternal interface using single cell transcriptomics - 10x data
Submitted on 26 March 2018, released on 2 October 2018, last updated on 27 November 2018
To explore the interactions between the range of maternal and fetal placental cell types present, we profiled the transcriptomes of more than 50,000 single cells from matched first trimester samples of maternal blood and decidua, as well as fetal cells from the placenta itself. RNA-seq was done using the standard 10x chromium v2 chemistry.
RNA-seq of coding RNA, cell type comparison design
Single-cell reconstruction of the early maternal-fetal interface in humans. Vento-Tormo R, Efremova M, Botting RA, Turco MY, Vento-Tormo M, Meyer KB, Park JE, Stephenson E, Pola?ski K, Goncalves A, Gardner L, Holmqvist S, Henriksson J, Zou A, Sharkey AM, Millar B, Innes B, Wood L, Wilbrey-Clark A, Payne RP, Ivarsson MA, Lisgo S, Filby A, Rowitch DH, Bulmer JN, Wright GJ, Stubbington MJT, Haniffa M, Moffett A, Teichmann SA. 563(7731):347-353 (2018), PMID:30429548