E-MTAB-5724 - Molecular subtyping of breast cancer by transcription profiling

Status
Last updated on 1 December 2017, released on 1 December 2017
Organism
Homo sapiens
Samples (522)
Array (1)
Protocols (6)
Description
Breast cancer was one of the first cancer types where molecular subtyping led to explanation of interpersonal heterogeneity and resulted in improvement of treatment regimen. Several multigene classifiers have been developed and in particular those defining molecular signatures of early breast cancers possess significant prognostic information. Hence since 2014, molecular subtyping of primary breast cancers was implemented as a part of routine diagnostics with direct impact of therapy assignment. In this study, we evaluate direct and potential benefits of molecular subtyping in low-risk breast cancers as well as present the advantages of a robust molecular signature in regard to patient work-up among high-risk breast cancers.
Experiment type
transcription profiling by array 
Contacts
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-5724.idf.txt
Sample and data relationshipE-MTAB-5724.sdrf.txt
Raw data (14)Click to browse raw data
Array designA-AFFY-44.adf.txt