E-MTAB-5686 - Determination of effects of propionate on gene expression in human cerebromicrovascular endothelial cell line hCMEC/D3
Status | Submitted on 8 March 2017, last updated on 2 March 2018, released on 5 March 2018 | ||||||||||
Organism | Homo sapiens | ||||||||||
Samples (6) | |||||||||||
Array (1) | |||||||||||
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Description | The experiment was designed to look at the effect (on gene expression) of exposing human cerebromicrovascular endothelial cell line hCMEC/D3 to propionate (3 micromolar) for 24 h, to determine if circulating metabolites have the potential to affect integrity of the blood-brain barrier. | ||||||||||
Experiment types | transcription profiling by array, compound treatment design | ||||||||||
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Citation | Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier. Hoyles L, Snelling T, Umlai UK, Nicholson JK, Carding SR, Glen RC, McArthur S. 6(1):55 (2018), PMID:29562936 | ||||||||||
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