E-MTAB-5686 - Determination of effects of propionate on gene expression in human cerebromicrovascular endothelial cell line hCMEC/D3

Status
Submitted on 8 March 2017, last updated on 2 March 2018, released on 5 March 2018
Organism
Homo sapiens
Samples (6)
Array (1)
Protocols (6)
Description
The experiment was designed to look at the effect (on gene expression) of exposing human cerebromicrovascular endothelial cell line hCMEC/D3 to propionate (3 micromolar) for 24 h, to determine if circulating metabolites have the potential to affect integrity of the blood-brain barrier.
Experiment types
transcription profiling by array, compound treatment design
Contact
Citation
Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier. Hoyles L, Snelling T, Umlai UK, Nicholson JK, Carding SR, Glen RC, McArthur S. 6(1):55 (2018), PMID:29562936
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-5686.idf.txt
Sample and data relationshipE-MTAB-5686.sdrf.txt
Raw data (1)E-MTAB-5686.raw.1.zip
Array designA-GEOD-10558.adf.txt