E-MTAB-4028 - Transcription profiling by array of Chicken Embryo Fibroblasts (CEF) and DF-1 in response to recombinant chicken chIFN-α and infection with Infectious Bursal Disease Virus (IBDV)
Submitted on 22 November 2012, last updated on 5 November 2015, released on 15 January 2016
The spontaneously immortalised chicken DF-1 cell line is rapidly replacing its progenitor primary chicken embryo fibroblasts (CEF) in studies on avian viruses but no comprehensive study has as yet been reported comparing their immune phenotype. We conducted microarray analysis of the DF-1 and CEF, in both normal and stimulated conditions using recombinant chicken chIFN-α and the CEF-adapted infectious bursal disease virus vaccine strain PBG98.
transcription profiling by array, compound treatment design, reference design, replicate design, stimulus or stress design