E-MTAB-3346 - Single-cell transcriptome sequencing from mouse mTECs

Status
Submitted on 19 February 2015, released on 2 August 2015, last updated on 28 August 2015
Organism
Homo sapiens, Mus musculus
Samples (345)
Protocols (7)
Description
Promiscuous gene expression (pGE) of tissue-restricted antigens in medullary thyme ephitelial cells (mTECs) is essential for self-tolerance induction and to prevent autoimmunity. We sequenced single mTEC transcriptomes to explore gene expression heterogeneity and to discover patterns of regulation of pGE.
Experiment types
RNA-seq of coding RNA from single cells, population based design
Contact
Citation
Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells. Brennecke P, Reyes A, Pinto S, Rattay K, Nguyen M, Küchler R, Huber W, Kyewski B, Steinmetz LM.  (2015), PMID:26237553
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-MTAB-3346.idf.txt
Sample and data relationshipE-MTAB-3346.sdrf.txt
Processed data (1)E-MTAB-3346.processed.1.zip
Additional data (1)E-MTAB-3346.additional.1.zip
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