E-MTAB-2232 - Genetics of gene expression across innate immune stimulation in primary monocytes
Released on 26 March 2014, last updated on 23 November 2018
Gene expression arrays and genotyping data in primary human monocytes from healthy individuals of European ancestry that have either been unstimulated (naive) or exposed to IFN gamma (24h) or Lipopolysaccharide (2 or 24h duration).
transcription profiling by array, co-expression, ex vivo, individual genetic characteristics
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression. Fairfax BP, Humburg P, Makino S, Naranbhai V, Wong D, Lau E, Jostins L, Plant K, Andrews R, McGee C, Knight JC. , PMID:24604202
Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes. Naranbhai V, Fletcher HA, Tanner R, OShea MK, McShane H, Fairfax BP, Knight JC, Hill AV. :732-732 (2013)
Genomic modulators of gene expression in human neutrophils. Vivek Naranbhai1*, Benjamin P. Fairfax1*, Seiko Makino1, Peter Humburg1, Daniel Wong1, Esther Ng1, Adrian V.S. Hill1, Julian C. Knight1*. , PMID:26151758