E-MTAB-1548 - Transcription profiling by array of peripheral blood patients with sepsis, systemic inflammatory response syndrome and healthy individuals to identify a biomarker of sepsis
Released on 15 March 2014, last updated on 22 February 2016
The peripheral whole-blood transcriptome analysis has been used to the identification of biomarkers in different clinical syndromes. The ability to simultaneously measure the gene expression levels of the whole transcriptome is providing a broader view of clinical syndromes such as sepsis. The aim of this study was to assess the gene expression profiles of post-surgical patients with septic shock compared with patients without sepsis.
transcription profiling by array, co-expression design, disease state design, in vivo design
Transcriptomic evidence of impaired immunoglobulin G production in fatal septic shock. Raquel Almansa, Eduardo Tamayo, María Heredia, Sandra Gutierrez, Patricia Ruiz, Elisa Alvarez, Esther Gomez-Sanchez, David Andaluz-Ojeda, Rafael Ceña, Lucia Rico, et al. , Europe PMC 24388659
Transcriptomic correlates of organ failure extent in sepsis. Raquel Almansa, María Heredia-Rodríguez, Esther Gomez-Sanchez, David Andaluz-Ojeda, Verónica Iglesias, Lucia Rico, Alicia Ortega, Estefanía Gomez-Pesquera, Pilar Liu, Marta Aragón, et al. , Europe PMC 25557485