E-MTAB-1294 - Transcription profiling by high throughput sequencing of human and mouse pancreatic islet-cells
Released on 3 October 2012, last updated on 3 May 2014
Homo sapiens, Mus musculus
The aim of this experiment was to obtain a detailed transcriptional landscape of human and mouse islet-cells, including strand information, as well an epigenetic map of transcriptionally active chromatin.
RNA-seq of coding RNA, is expressed, species
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes. Morán I, Akerman I, van de Bunt M, Xie R, Benazra M, Nammo T, Arnes L, Nakić N, García-Hurtado J, Rodríguez-Seguí S, Pasquali L, Sauty-Colace C, Beucher A, Scharfmann R, van Arensbergen J, Johnson PR, Berry A, Lee C, Harkins T, Gmyr V, Pattou F, Kerr-Conte J, Piemonti L, Berney T, Hanley N, Gloyn AL, Sussel L, Langman L, Brayman KL, Sander M, McCarthy MI, Ravassard P, Ferrer J. Cell Metab 16(4):435-448 (2012), Europe PMC 23040067