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E-GEOD-64595 - Comparison of gene expression profiles between the CD110+ tumor initiating cells from primary colorectal tumors and their liver metastases

Status
Released on 1 January 2015, last updated on 24 January 2015
Organism
Homo sapiens
Samples (12)
Array (1)
Protocols (17)
Description
We established an in vivo model of organ-specific colorectal cancer metastasis and demonstrated that the CD110+ tumor initiating cells contribute for colorectal liver metastasis. To gain a deeper understanding of its metastatic capacity, we performed a genome-wide transcriptome analysis on the CD110+ tumor cells derived from primary colon xenografts and their matched liver metastases. Results provide important information of the responses of the CD110+ cells during the process of liver colonization. Total RNA obtained from the CD110+ cells sorted from primary colorectal tumors (CRC102-PT and CRC108-PT) compared to those from the corresponding liver metastases (CRC102-LM and CRC108-LM).
Experiment type
transcription profiling by array 
Contacts
Li Qingquan <061101040@fudan.edu.cn>, WenChao Gao, Zhengming Wu
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-64595.idf.txt
Sample and data relationshipE-GEOD-64595.sdrf.txt
Raw data (1)E-GEOD-64595.raw.1.zip
Processed data (1)E-GEOD-64595.processed.1.zip
Additional data (1)E-GEOD-64595.additional.1.zip
Array designA-GEOD-10558.adf.txt
Links