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E-GEOD-64491 - DNA methylation profiles of 30 tissues from a 112 year old woman

Status
Released on 3 June 2015, last updated on 6 June 2015
Organism
Homo sapiens
Samples (64)
Array (1)
Protocols (6)
Description
The main goal of the study was to measure the epigenetic age (also known as DNA methylation age) of these tissues. Toward this end, we used the epigenetic clock software described in Horvath S (n=2013) DNA methylation age of human tissues and cell types. Genome Biology.2013, 14:R115. DOI: 10.1186/10.1186/gb-2013-14-10-r115 PMID: 24138928 Human DNA methylation Beadchip v1.2 was used to obtain n=64 Illumina DNA methylation arrays from 30 tissues. For each of the following tissues, we obtained at least 2 replicates: adipose, adrenal gland, aorta, bone, bone-marrow, breast, buccal cells, cartilage, cerebellum, colon, diaphragm, esophagus , frontal cortex, kidney, heart, hippocampus, liver, lung, lymph node, midbrain, muscle, occipital cortex, pancreas, pericardium skin, spleen, stomach, temporal cortex, thyroid, whole blood.
Experiment type
methylation profiling by array 
Contacts
Citation
The cerebellum ages slowly according to the epigenetic clock. Horvath S, Mah V, Lu AT, Woo JS, Choi OW, Jasinska AJ, Riancho JA, Tung S, Coles NS, Braun J, Vinters HV, Coles LS.
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-64491.idf.txt
Sample and data relationshipE-GEOD-64491.sdrf.txt
Processed data (2)E-GEOD-64491.processed.1.zip, E-GEOD-64491.processed.2.zip
Additional data (1)E-GEOD-64491.additional.1.zip
Array designA-GEOD-13534.adf.txt
Links