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E-GEOD-63454 - miR-487b, miR-3963 and miR-6412 delayed myogenic differentiation in C2C12 mouse myoblast-derived cells

Status
Released on 24 November 2015, last updated on 28 November 2015
Organism
Mus musculus
Samples (3)
Array (1)
Protocols (7)
Description
We newly identified skeletal muscle differentiation-associated miRNAs by comparing miRNA expression profile between C2C12 cell and Wnt4-overexpressing C2C12 cell. miR-487b, miR-3963 and miR-6412 are significantly down-regulated in differentiating C2C12 cells, and transfection of their mimics resulted in reduced expression of myogenic differentiation markers including Troponin T, myosin heavy chain fast and slow type. Single analysis for each condition (proliferating C2C12 cells, differentiating C2C12 cells, proliferating Wnt4-overexpressing C2C12 subline cells
Experiment type
transcription profiling by array 
Contacts
Citation
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-63454.idf.txt
Sample and data relationshipE-GEOD-63454.sdrf.txt
Raw data (1)E-GEOD-63454.raw.1.zip
Processed data (1)E-GEOD-63454.processed.1.zip
Array designA-GEOD-18466.adf.txt
Links