Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-59834 - Genes regulated by SET7/9 knockdown in gastric cancer cells
Released on 24 July 2015, last updated on 19 August 2015
Expression of SET7/9, a histone methyltransferase, was frequently reduced in cultured and primary gastric cancers. To identify the SET7/9 target genes in gastric cancer, we performed siRNA-based knockdown of SET7/9 in MKN74 and MKN45 cells and then examined significant expression changes of genes by microarray. Transfection of SET7/9 siRNA into MKN74 and MKN45 cells were performed by electroporation. After 48hrs, cells were harvested. Total RNA was used for cDNA microarray.
transcription profiling by array
Yoshimitsu Akiyama <firstname.lastname@example.org>, S Shimada, T Nishikawaji, Y Akiyama, Y Yuasa