Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-59006 - Fluvastatin-induced differential global gene expression in human malignant MCF-7 breast cancer cells
Released on 1 September 2014, last updated on 6 September 2014
The current study analyzed the altered expression profiles of genes that are responsible for fluvastatin-induced breast cancer cell death in MCF-7 cells (ER+ve luminal breast cancer cells). Some of these altered gene expressions were further inter connceted to various pathways which may eventually be recognised as drug targets/ biomarkers in statin-sensitve breast cancer patients. To understand the differential gene expression profile in fluvastatin treated (24 h) malignant breast cancer cells with untreated malignant breast cancer cells.
transcription profiling by array
Anantha K Kanugula, Paradesi N Gollavilli, Sandhya K Pemmasani, Srigiridhar Kotamraju