Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.

E-GEOD-57270 - Genomic analysis of low-grade serous ovarian carcinomas [ILOE]

Status
Released on 1 October 2014, last updated on 4 October 2014
Organism
Homo sapiens
Samples (30)
Array (1)
Protocols (7)
Description
Low-grade serous ovarian carcinomas are typically Ras-pathway mutated, TP53 wild-type, have limited chromosomal aberration, and are frequently associated with borderline tumors. By contrast, high-grade serous ovarian carcinoma lack Ras-pathway mutations, are invariably TP53 mutated, show widespread genomic change, and are commonly BRCA-pathway disrupted. We sought to identify differences in genomic copy number changes in borderline and invasive components of serous carcinoma. Borderline and invasive tumor components were profiled from patients with LGSC
Experiment type
comparative genomic hybridization by array 
Contacts
Dariush Etemadmoghadam <dariush.etemadmoghadam@petermac.org>, Anna deFazio, Catherine Emmanuel, David Bowtell, Joshy George, Yoke-Eng Chiew
MIAME
PlatformsProtocolsVariablesProcessedRaw
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