E-GEOD-5258 - Transcription profiling by array of human cell lines after treatment with various small molecules
Released on 6 December 2008, last updated on 19 May 2014
A reference collection of genome-wide transcriptional expression data for bioactive small molecules. Experiment Overall Design: The current collection (build01) contains data for 164 distinct small molecules applied to freely cycling human cell lines, represented by 453 individual treatment and matched vehicle control pairs.
transcription profiling by array, co-expression, compound treatment
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Justin Lamb, Emily D Crawford, David Peck, Joshua W Modell, Irene C Blat, Matthew J Wrobel, Jim Lerner, Jean-Philippe Brunet, Aravind Subramanian, Kenneth N Ross, Michael Reich, Haley Hieronymus, Guo Wei, Scott A Armstrong, Stephen J Haggarty, Paul A Clemons, Ru Wei, Steven A Carr, Eric S Lander, Todd R Golub. , Europe PMC 17008526