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E-GEOD-49218 - Gene regulation by CBP-p300 in the lens placode - E10.5

Released on 23 September 2013, last updated on 3 June 2014
Mus musculus
Samples (6)
Array (1)
Protocols (7)
Wild type or CBP/p300 fx/fx; Pax6-Cre-positive (CBP/p300-/-) surface ectoderm from E10.5 mouse embryos was laser micodissected from three embryos of each genotype. Total RNA was purified, pooled for each genotype and triplicate samples were reverse transcribed and amplified using a NuGEN kit. cDNA was biotinylated and hybridized to Illumina Mouse6v2.0 bead arrays. Three wild type and three knockout embryos were used. The RNA from embryos of the same genotype was purified and pooled and triplicate samples were amplified and used for microarray analysis.
Experiment type
transcription profiling by array 
David Cy Beebe <>, David C Beebe, Jie Huang, Ying Liu
Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300. Wolf L, Harrison W, Huang J, Xie Q, Xiao N, Sun J, Kong L, Lachke SA, Kuracha MR, Govindarajan V, Brindle PK, Ashery-Padan R, Beebe DC, Overbeek PA, Cvekl A. , PMID:24038357
Investigation descriptionE-GEOD-49218.idf.txt
Sample and data relationshipE-GEOD-49218.sdrf.txt
Processed data (1)
Additional data (1)
Array designA-MEXP-1175.adf.txt