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E-GEOD-45735 - Changes in PBMC gene expression profiles after influenza vaccination in healthy human subjects

Released on 7 August 2013, last updated on 5 September 2013
Homo sapiens
Samples (55)
Protocols (3)
Daily sampling of peripheral blood from human subjects vaccinated for influenza was done immediately before vaccination and for 10 days after vaccination. Temporal patterns of gene expression, determined by RNA-seq, in unfractionated PBMC suggested migration of myeloid/dendritic cell lineage cells one day after vaccination. Five subjects, 11 time points per subject (pre-vaccination and daily for 10 days post-vaccination)
Experiment type
RNA-seq of coding RNA 
Stephen Welle <>, Alicia D Henn, Martin S Zand, Stephen L Welle
High-resolution temporal response patterns to influenza vaccine reveal a distinct human plasma cell gene signature. Henn AD, Wu S, Qiu X, Ruda M, Stover M, Yang H, Liu Z, Welle SL, Holden-Wiltse J, Wu H, Zand MS. , PMID:23900141
Exp. designProtocolsVariablesProcessedSeq. reads
Investigation descriptionE-GEOD-45735.idf.txt
Sample and data relationshipE-GEOD-45735.sdrf.txt
Additional data (1)