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E-GEOD-23556 - Mx-Cre mediated deletion of SRF in murine hematopoietic LSK (Lin-Sca1+c-Kit+) cells

Status
Released on 12 August 2010, last updated on 27 March 2012
Organism
Mus musculus
Samples (6)
Array (1)
Protocols (8)
Description
Analysis of hematopoietic LSK(Lin-Sca1+c-Kit+) cells lacking the Serum response factor (SRF) gene. Results provide insight into the role of SRF in regulating genetic programs important for hematopoietic stem cell development Comparison of the gene expression profile between murine Lin-Sca1+c-Kit+ cells from Mx-Cre C57BL/6 Srf WT (3) and C57BL/6 Srf KO (3). Cells were sorted by flow cytometry and RNA was harvested and hybridized to Affymetrix MOE430A.
Experiment type
transcription profiling by array 
Contacts
Citation
The transcription factor SRF regulates hematopoietic stem cells adhesion. Ragu C, Elain G, Mylonas E, Ottolenghi C, Cagnard N, Daegelen D, Passegué E, Vainchenker W, Bernard OA, Penard-Lacronique V. , PMID:20709909
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-23556.idf.txt
Sample and data relationshipE-GEOD-23556.sdrf.txt
Raw data (1)E-GEOD-23556.raw.1.zip
Processed data (1)E-GEOD-23556.processed.1.zip
Array designA-AFFY-45.adf.txt
R ExpressionSetE-GEOD-23556.eSet.r
Links