Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-22886 - Expression profiles from a variety of resting and activated human immune cells
Released on 13 July 2010, last updated on 27 March 2012
Immune cell-specific expression is one indication of the importance of a gene's role in the immune response. In order to identify such patterns, we set out to broadly profile gene expression in a variety of immune cells. We isolated twelve different types of human leukocytes from peripheral blood and bone marrow, treated them to induce activation and/or differentiation, and profiled their gene expression before and after treatment. The twelve cell types are: B cells, CD14+ cells, CD4+ CD45RO+ CD45RA- T cells, CD4+ T cells, CD8+ T cells, IgG/IgA memory B cells, IgM memory B cells, Monocytes, NK cells, Neutrophils, Plasma cells from bone marrow, and Plasma cells from PBMC.
transcription profiling by array
Alex Abbas <firstname.lastname@example.org>, Alexander R Abbas, Andrew C Chan, Austin Gurney, Daryl Baldwin, Flavius Martin, Hilary F Clark, Menno van Lookeren Campagne, P M Williams, Paul Godowski, Sherman Fong, Wenjun Ouyang, Yan Ma
Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data. Abbas AR, Baldwin D, Ma Y, Ouyang W, Gurney A, Martin F, Fong S, van Lookeren Campagne M, Godowski P, Williams PM, Chan AC, Clark HF. , PMID:15789058