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E-GEOD-11835 - Gene expression data in heifers with persistently infected (PI) or transiently infected (TI) fetuses
Released on 15 June 2009, last updated on 27 March 2012
The response to the presence of the ncpBVDV-infected PI or TI fetus is expected to provide information on the impact of the PI fetus on the immune response of the dam Fetal PI infection was induced by intranasal inoculation of pregnant heifers with ncpBVDV on day 75 of gestation. Fetal transient infection (TI) was induced by infection of pregnant heifers with ncpBVDV on day 175 of gestation. Control heifers were kept uninfected. Blood samples from pregnant heifers of the PI and control groups were collected on day 160 of gestation. Blood samples of PI, TI and healthy fetus carrying heifers were collected for microarray on day 190 of gestation.
transcription profiling by array
Kate McInnerney <firstname.lastname@example.org>, Austin Kathleen, Bielefeldt-Ohmann Helel, Han Hyungchul, Hansen Thomas, Ptitsyn Andrey, Smirnova Natalia, VanCampen Hana, vanOlphen Alberto
Persistent fetal infection with bovine viral diarrhea virus differentially affects maternal blood cell signal transduction pathways. Smirnova NP, Ptitsyn AA, Austin KJ, Bielefeldt-Ohmann H, Van Campen H, Han H, van Olphen AL, Hansen TR. , PMID:19018046