Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.

E-GEOD-11775 - Transcription profiling of regulatory T cells (Treg) and Effector CD4+ T cells in healthy B6 mice and sick mice with scurfy mutation - Foxp3-deficient Treg cells do not revert into conventional Effector CD4+ T cells but constitute a unique cell subset

Status
Released on 4 September 2009, last updated on 10 June 2011
Organism
Mus musculus
Samples (12)
Array (1)
Protocols (3)
Description
Gene expression profiles were compared between regulatory T cells (Treg) and Effector CD4+ T cells in healthy B6 mice and sick mice with scurfy mutation. We used microarrays to elucidate the molecular mechanisms underlying the suppression function of the Treg cells. Experiment Overall Design: To identify candidate genes that might be related to the suppressive activity, the Treg cells expressing functional and mutant Foxp3 transcription factor were compared
Experiment types
transcription profiling by array, unknown experiment type
Contact
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-11775.idf.txt
Sample and data relationshipE-GEOD-11775.sdrf.txt
Raw data (1)E-GEOD-11775.raw.1.zip
Processed data (1)E-GEOD-11775.processed.1.zip
Experiment designE-GEOD-11775.biosamples.png, E-GEOD-11775.biosamples.svg
Array designA-AFFY-45.adf.txt
R ExpressionSetE-GEOD-11775.eSet.r
Links