Mannosyl-oligosaccharide 1,2-alpha-mannosidase (M-CSA:19)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this chain

The residue id shown is the one in the PDB sequence. This may be different from the resid given by the author of the PDB file.

PDB sequences homologous to 1x9d

Reference PDB chains/ identical chains Homologous PDB chains Glu132(99)A Asp275(242)A Arg136(103)A Glu330(169)A Arg334(173)A Asp463(302)A Glu599(438)A Glu435(397)A
1x9d(A)
PfamFunTree
1fo3(A)
PfamFunTree
1fo2(A)
PfamFunTree
Glu91 Arg95 Asp224 Glu360
1x9d(A)
PfamFunTree
1hcu(B,D,A,C)
PfamFunTree
Glu100 Arg104 Asp245 Glu393
1x9d(A)
PfamFunTree
1dl2(A)
PfamFunTree
Glu99 Arg103 Asp242 Glu397
1x9d(A)
PfamFunTree
1g6i(A)
PfamFunTree
Glu133 Arg137 Asp276 Glu431
1x9d(A)
PfamFunTree
1kkt(B,A)
PfamFunTree
1kre(B,A)
PfamFunTree
1krf(B,A)
PfamFunTree
Glu122 Arg126 Asp267 Glu409
1x9d(A)
PfamFunTree
4ayp(A)
PfamFunTree
4ayo(A)
PfamFunTree
4ayq(A)
PfamFunTree
5ne5(A)
PfamFunTree
5meh(A)
PfamFunTree
4ayr(A)
PfamFunTree
Glu98 Arg102 Asp226 Glu342
1x9d(A)
PfamFunTree
5kkb(B,A)
PfamFunTree
Glu107 Arg111 Asp240 Glu374
1x9d(A)
PfamFunTree
1nxc(A)
PfamFunTree
Glu105 Arg109 Asp238 Glu372
1x9d(A)
PfamFunTree
1x9d(A)
PfamFunTree
x x x x
1x9d(A)
PfamFunTree
1fmi(A)
PfamFunTree
Glu91 Arg95 Asp224 Glu360
1x9d(A)
PfamFunTree
2ri8(B,A)
PfamFunTree
2ri9(B,A)
PfamFunTree
Glu87 Arg91 Asp232 Glu374
1x9d(A)
PfamFunTree
5kij(A)
PfamFunTree
Glu86 Arg90 Asp219 Glu355
1x9d(A)
PfamFunTree
5kk7(B,A)
PfamFunTree
Glu86 Arg90 Asp219 Glu355