PDBsum entry 5tsk

Virus

PDB id: 5tsk

Contents

Protein chain

219 a.a.

PDB id:

5tsk

Name:

Virus

Title:

Molecular dynamics flexible fitting model of coxsackievirus a16 empty procapsid vp1 subunit

Structure:

Coxsackievirus a16 empty procapsid vp1 subunit. Chain: a

Source:

Coxsackievirus a16. Organism_taxid: 31704. Strain: sz05. Cell_line: vero

Authors:

C.Fan,Y.Cong,X.Ye,Z.Huang

Key ref:

F.Chen et al. Structural alteration and surface modifi cation of coxsackievirus a16 capsids by beta-Propiolactone trea. J virol, .

Date:

29-Oct-16 Release date: 01-Feb-17

Protein chain

A9LXZ4  (A9LXZ4_9ENTO) -  Genome polyprotein from Coxsackievirus A16

Seq: 2193 a.a.

Struc: 219 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class 2: E.C.2.7.7.48 - RNA-directed Rna polymerase.
• Reaction: RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
• Enzyme class 3: E.C.3.4.22.28 - picornain 3C.
• Reaction: Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
• Enzyme class 4: E.C.3.4.22.29 - picornain 2A.
• Reaction: Selective cleavage of Tyr-|-Gly bond in the picornavirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
• Enzyme class 5: E.C.3.6.1.15 - nucleoside-triphosphate phosphatase.
• Reaction: a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H⁺

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site