PDBsum entry 5ktw

Transferase

PDB id: 5ktw

Contents

Protein chains

114 a.a.

Ligands

6XG ×3

EDO ×8

Waters ×594

References listed in PDB file

Key reference

• Title: Discovery of a potent and selective in vivo probe (gne-272) for the bromodomains of cbp/ep300.
• Authors: T.D.Crawford, F.A.Romero, K.W.Lai, V.Tsui, A.M.Taylor, G.De leon boenig, C.L.Noland, J.Murray, J.Ly, E.F.Choo, T.L.Hunsaker, E.W.Chan, M.Merchant, S.Kharbanda, K.E.Gascoigne, S.Kaufman, M.H.Beresini, J.Liao, W.Liu, K.X.Chen, Z.Chen, A.R.Conery, A.Côté, H.Jayaram, Y.Jiang, J.R.Kiefer, T.Kleinheinz, Y.Li, J.Maher, E.Pardo, F.Poy, K.L.Spillane, F.Wang, J.Wang, X.Wei, Z.Xu, Z.Xu, I.Yen, L.Zawadzke, X.Zhu, S.Bellon, R.Cummings, A.G.Cochran, B.K.Albrecht, S.Magnuson.
• Ref.: J Med Chem, 2016, 59, 10549-10563. [DOI no: 10.1021/acs.jmedchem.6b01022]
• PubMed id: 27682507

Abstract

No abstract given.