PDBsum entry 5emq

Transcription/DNA

PDB id: 5emq

Contents

Protein chains

70 a.a.

DNA/RNA

Metals

_ZN ×4

Waters ×35

PDB id:

5emq

Name:

Transcription/DNA

Title:

Transcription factor grdbd and gre complex

Structure:

DNA (5'- d( Cp Cp Ap Gp Ap Ap Cp Ap Tp Gp Ap Tp Gp Tp Tp Cp Tp G)-3'). Chain: c. Engineered: yes. DNA (5'- d( Cp Cp Ap Gp Ap Ap Cp Ap Tp Cp Ap Tp Gp Tp Tp Cp Tp G)-3'). Chain: d. Engineered: yes. Glucocorticoid receptor.

Source:

Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human. Organism_taxid: 9606. Gene: nr3c1, grl. Expressed in: escherichia coli-pichia pastoris shuttle vector ppphis4.

Resolution:

2.30Å R-factor: 0.201 R-free: 0.224

Authors:

T.Lian,J.Jin,X.Su

Key ref:

T.Lian et al. The effects of cytosine methylation on general transc factors. To be published, .

Date:

06-Nov-15 Release date: 29-Jun-16

Protein chains

P04150  (GCR_HUMAN) -  Glucocorticoid receptor from Homo sapiens

Seq: 777 a.a.

Struc: 70 a.a.

DNA/RNA chains

C-C-A-G-A-A-C-A-T-G-A-T-G-T-T-C-T-G 18 bases

C-C-A-G-A-A-C-A-T-C-A-T-G-T-T-C-T-G 18 bases

Enzyme reactions

• Enzyme class: E.C.?