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PDBsum entry 5zid

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protein ligands Protein-protein interface(s) links
Hydrolase PDB id
5zid

 

 

 

 

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Contents
Protein chains
727 a.a.
Ligands
NAG-MAN-MAN-MAN
NAG ×2
9EL ×2
Waters ×43
PDB id:
5zid
Name: Hydrolase
Title: Crystal structure of human dpp-iv in complex with hl2
Structure: Dipeptidyl peptidase 4. Chain: a, b. Fragment: dipeptidyl peptidase 4 soluble form. Synonym: adabp,adenosine deaminase complexing protein 2,adcp-2, dipeptidyl peptidase iv,dpp iv,t-cell activation antigen cd26,tp103. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dpp4, adcp2, cd26. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Resolution:
3.00Å     R-factor:   0.194     R-free:   0.253
Authors: L.Zhu,H.Li,F.Wu
Key ref: L.Zhu et al. Crystal structure of human dpp-Iv in complex with hl2. To be published, .
Date:
14-Mar-18     Release date:   20-Mar-19    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P27487  (DPP4_HUMAN) -  Dipeptidyl peptidase 4 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
766 a.a.
727 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: E.C.3.4.14.5  - dipeptidyl-peptidase Iv.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Release of an N-terminal dipeptide, Xaa-Xbb-|-Xcc, from a polypeptide, preferentially when Xbb is Pro, provided Xcc is neither Pro nor hydroxyproline.

 

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