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PDBsum entry 5paq
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protein ligands metals Protein-protein interface(s) links
Hydrolase/hydrolase inhibitor PDB id
5paq

 

 

 

 

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Contents
Protein chains
58 a.a.
250 a.a.
Ligands
GOL ×2
SO4
7ZA
Metals
_CL ×3
_CA
Waters ×385
PDB id:
5paq
Name: Hydrolase/hydrolase inhibitor
Title: Crystal structure of factor viia in complex with 2-[(1- aminoisoquinolin-6-yl)amino]-2-(3-ethoxy-4-propan-2-yloxyphenyl)-1- (2-phenylpyrrolidin-1-yl)ethanone
Structure: Coagulation factor vii light chain. Chain: a. Synonym: proconvertin,serum prothrombin conversion accelerator,spca. Engineered: yes. Coagulation factor vii heavy chain. Chain: b. Synonym: proconvertin,serum prothrombin conversion accelerator,spca. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: f7. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.59Å     R-factor:   0.175     R-free:   0.194
Authors: M.Stihle,A.Mayweg,S.Roever,M.G.Rudolph
Key ref: A.Mayweg et al. Crystal structure of a factor viia complex. To be published, .
Date:
10-Nov-16     Release date:   21-Jun-17    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P08709  (FA7_HUMAN) -  Coagulation factor VII from Homo sapiens
Seq:
Struc: 		466 a.a.
58 a.a.
Protein chain
Pfam   ArchSchema ?
P08709  (FA7_HUMAN) -  Coagulation factor VII from Homo sapiens
Seq:
Struc: 		466 a.a.
250 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: Chains A, B: E.C.3.4.21.21  - coagulation factor VIIa.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Hydrolyzes one Arg-|-Ile bond in factor X to form factor Xa.

 

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