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PDBsum entry 5pae
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protein ligands metals Protein-protein interface(s) links
Hydrolase/hydrolase inhibitor PDB id
5pae

 

 

 

 

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Contents
Protein chains
56 a.a.
247 a.a.
Ligands
SO4 ×5
GOL ×2
7YA
Metals
_CA
Waters ×376
PDB id:
5pae
Name: Hydrolase/hydrolase inhibitor
Title: Crystal structure of factor viia in complex with (2s)-2-hydroxy-n-[[3- [5-hydroxy-4-(1h-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1- yl]phenyl]methyl]propanamide
Structure: Coagulation factor vii light chain. Chain: a. Synonym: proconvertin,serum prothrombin conversion accelerator,spca. Engineered: yes. Coagulation factor vii heavy chain. Chain: b. Synonym: proconvertin,serum prothrombin conversion accelerator,spca. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: f7. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.45Å     R-factor:   0.179     R-free:   0.188
Authors: M.Stihle,A.Mayweg,S.Roever,M.G.Rudolph
Key ref: A.Mayweg et al. Crystal structure of a factor viia complex. To be published, .
Date:
10-Nov-16     Release date:   21-Jun-17    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P08709  (FA7_HUMAN) -  Coagulation factor VII from Homo sapiens
Seq:
Struc: 		466 a.a.
56 a.a.
Protein chain
Pfam   ArchSchema ?
P08709  (FA7_HUMAN) -  Coagulation factor VII from Homo sapiens
Seq:
Struc: 		466 a.a.
247 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: Chains A, B: E.C.3.4.21.21  - coagulation factor VIIa.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Hydrolyzes one Arg-|-Ile bond in factor X to form factor Xa.

 

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