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PDBsum entry 5j3j
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PDB id:
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Hydrolase
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Title:
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Crystal structure of human dpp-iv in complex with hl1
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Structure:
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Dipeptidyl peptidase 4. Chain: a, b. Synonym: adabp,adenosine deaminase complexing protein 2,adcp-2, dipeptidyl peptidase iv,dpp iv,t-cell activation antigen cd26,tp103. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: dpp4, adcp2, cd26. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
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Resolution:
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2.75Å
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R-factor:
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0.238
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R-free:
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0.298
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Authors:
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F.Wu,H.Li,Z.Zhao,L.Zhu,H.Xu,S.Li
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Key ref:
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F.Wu
et al.
Crystal structure of human dpp-Iv in complex with hl1.
To be published,
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Date:
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31-Mar-16
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Release date:
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05-Apr-17
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PROCHECK
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Headers
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References
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P27487
(DPP4_HUMAN) -
Dipeptidyl peptidase 4 from Homo sapiens
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Seq:
Struc:
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766 a.a.
727 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.3.4.14.5
- dipeptidyl-peptidase Iv.
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Reaction:
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Release of an N-terminal dipeptide, Xaa-Xbb-|-Xcc, from a polypeptide, preferentially when Xbb is Pro, provided Xcc is neither Pro nor hydroxyproline.
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Links
