PDBsum entry 4k8h

Oxidoreductase

PDB id: 4k8h

Contents

Protein chain

399 a.a.

Ligands

FMN

07V

PGE

1PE

Metals

_CL ×2

_NA ×2

Waters ×542

PDB id:

4k8h

Name:

Oxidoreductase

Title:

Oye1-w116v complexed with (r)-carvone

Structure:

NADPH dehydrogenase 1. Chain: a. Synonym: old yellow enzyme 1. Engineered: yes. Mutation: yes

Source:

Saccharomyces pastorianus. Lager yeast. Organism_taxid: 27292. Gene: oye1. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.55Å R-factor: 0.128 R-free: 0.162

Authors:

B.Sullivan,Y.A.Pompeu,J.D.Stewart

Key ref:

Y.A.Pompeu et al. (2013). X‑. Acs catalysis, 3, 2376.

Date:

18-Apr-13 Release date: 09-Oct-13

Protein chain

Q02899  (OYE1_SACPS) -  NADPH dehydrogenase 1 from Saccharomyces pastorianus

Seq: 400 a.a.

Struc: 399 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.1.6.99.1 - Nadph dehydrogenase.
• Reaction: A + NADPH + H⁺ = AH2 + NADP⁺
• Cofactor: FMN or FAD

FMN (Bound ligand (Het Group name = FMN) corresponds exactly) or FAD

Molecule diagrams generated from .mol files obtained from the KEGG ftp site