PDBsum entry 4icz

Hydrolase

PDB id: 4icz

Contents

Protein chain

292 a.a.

Ligands

ASN-LEU-PTR-PTR-TRP

Waters ×118

PDB id:

4icz

Name:

Hydrolase

Title:

Her2 1221/1222 phosphorylation regulated by ptpn9

Structure:

Tyrosine-protein phosphatase non-receptor type 9. Chain: a. Fragment: unp residues 277-582. Synonym: protein-tyrosine phosphatase meg2, ptpase meg2. Engineered: yes. Her2. Chain: f. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn9. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans

Resolution:

1.90Å R-factor: 0.206 R-free: 0.249

Authors:

Y.F.Xu,H.M.Wang,C.H.Liu,X.Yu,J.P.Sun

Key ref:

Y.F.Xu et al. Her2 1221/1222 phosphorylation regulated by ptpn9. To be published, .

Date:

11-Dec-12 Release date: 11-Dec-13

Protein chain

P43378  (PTN9_HUMAN) -  Tyrosine-protein phosphatase non-receptor type 9 from Homo sapiens

Seq: 593 a.a.

Struc: 292 a.a.

Enzyme reactions

• Enzyme class: E.C.3.1.3.48 - protein-tyrosine-phosphatase.
• Reaction: O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site