Crystal structure of a loop deleted mutant of human madcam-1 d1d2 complexed with fab 10g3
Structure:
Mucosal addressin cell adhesion molecule 1. Chain: a, b. Synonym: madcam-1, hmadcam-1. Engineered: yes. 10g3 heavy chain. Chain: h, m. Engineered: yes. 10g3 light chain. Chain: l, n.
Source:
Homo sapiens. Human. Organism_taxid: 9606. Gene: madcam1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: 293s. Expression_system_organ: kidney. Mus musculus.
Resolution:
2.87Å
R-factor:
0.203
R-free:
0.253
Authors:
T.Springer,Y.Yu,J.Zhu
Key ref:
T.Springer
et al.
A different fold with an integrin-Binding loop specia for flexibility in mucosal addressin cell adhesion molecule-1.
To be published,
.
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