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PDBsum entry 3zd1
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Immune system
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PDB id
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3zd1
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PDB id:
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| Name: |
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Immune system
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Title:
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Structure of the two c-terminal domains of complement factor h related protein 2
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Structure:
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Complement factor h-related protein 2. Chain: a, b. Fragment: scr domains 3 and 4, residues 147-270. Synonym: fhr-2, ddesk59, h factor-like 3, h factor-like protein 2. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
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Resolution:
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2.00Å
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R-factor:
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0.212
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R-free:
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0.240
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Authors:
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J.J.E.Caesar,E.Goicoechea De Jorge,M.C.Pickering,S.M.Lea
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Key ref:
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E.Goicoechea de Jorge
et al.
(2013).
Dimerization of complement factor H-related proteins modulates complement activation in vivo.
Proc Natl Acad Sci U S A,
110,
4685-4690.
PubMed id:
DOI:
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Date:
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23-Nov-12
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Release date:
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13-Mar-13
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PROCHECK
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Headers
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References
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P36980
(FHR2_HUMAN) -
Complement factor H-related protein 2 from Homo sapiens
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Seq:
Struc:
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270 a.a.
124 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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DOI no:
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Proc Natl Acad Sci U S A
110:4685-4690
(2013)
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PubMed id:
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Dimerization of complement factor H-related proteins modulates complement activation in vivo.
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E.Goicoechea de Jorge,
J.J.Caesar,
T.H.Malik,
M.Patel,
M.Colledge,
S.Johnson,
S.Hakobyan,
B.P.Morgan,
C.L.Harris,
M.C.Pickering,
S.M.Lea.
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ABSTRACT
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Links
