PDBsum entry 3uci

Toxin

PDB id: 3uci

Contents

Protein chain

72 a.a.

Waters ×102

PDB id:

3uci

Name:

Toxin

Title:

Crystal structure of rhodostomin arlddl mutant

Structure:

Disintegrin. Chain: a. Synonym: disintegrin rhodostomin, rho, disintegrin kistrin, platelet aggregation activation inhibitor. Engineered: yes. Mutation: yes

Source:

Calloselasma rhodostoma. Malayan pit viper. Organism_taxid: 8717. Gene: rhod. Expressed in: pichia pastoris. Expression_system_taxid: 4922.

Resolution:

1.35Å R-factor: 0.147 R-free: 0.189

Authors:

J.H.Shiu,C.Y.Chen,Y.C.Chen,Y.T.Chang,Y.S.Chang,C.H.Huang,W.J.Chuang

Key ref:

J.H.Shiu et al. Design of integrin alphavbeta3-Specific disintegrin f cancer therapy. To be published, .

Date:

27-Oct-11 Release date: 21-Nov-12

Protein chain

P30403  (VM2RH_CALRH) -  Zinc metalloproteinase/disintegrin from Calloselasma rhodostoma

Seq: 478 a.a.

Struc: 72 a.a.*

* PDB and UniProt seqs differ at 7 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.4.24.- - ?????