PDBsum entry 3tpu

Immune system

PDB id: 3tpu

Contents

Protein chains

205 a.a.

240 a.a.

173 a.a.

Ligands

PHE-LEU-SER-PRO-PHE-TRP-PHE-ASP-ILE ×4

SO4 ×15

EDO

Waters ×4

PDB id:

3tpu

Name:

Immune system

Title:

42f3 p5e8/h2-ld complex

Structure:

42f3 alpha. Chain: a, c, g, m. Engineered: yes. 42f3 beta. Chain: b, d, h, n. Engineered: yes. H2-ld sbm2. Chain: i, e, k, q. Engineered: yes.

Source:

Mus musculus, homo sapiens. Organism_taxid: 10090, 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Mus musculus. Organism_taxid: 10090. Synthetic: yes. Other_details: genscript

Resolution:

3.10Å R-factor: 0.232 R-free: 0.258

Authors:

J.J.Adams,D.M.Kranz,K.C.Garcia

Key ref:

J.J.Adams et al. (2011). T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. Immunity, 35, 681-693. PubMed id: 22101157

Date:

08-Sep-11 Release date: 07-Dec-11

Protein chains

No UniProt id for this chain

Struc: 205 a.a.

Protein chains

No UniProt id for this chain

Struc: 240 a.a.

Protein chains

P01897  (HA1L_MOUSE) -  H-2 class I histocompatibility antigen, L-D alpha chain from Mus musculus

Seq: 362 a.a.

Struc: 173 a.a.*

* PDB and UniProt seqs differ at 9 residue positions (black crosses)

Immunity 35:681-693 (2011)

PubMed id: 22101157

T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.

J.J.Adams, S.Narayanan, B.Liu, M.E.Birnbaum, A.C.Kruse, N.A.Bowerman, W.Chen, A.M.Levin, J.M.Connolly, C.Zhu, D.M.Kranz, K.C.Garcia.

ABSTRACT

No abstract given.