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PDBsum entry 3thm
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Immune system
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PDB id
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3thm
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Contents |
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214 a.a.
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228 a.a.
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77 a.a.
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PDB id:
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Immune system
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Title:
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Crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
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Structure:
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Fab ep6b_b01, light chain. Chain: l. Engineered: yes. Fab ep6b_b01, heavy chain. Chain: h. Engineered: yes. Tumor necrosis factor receptor superfamily member 6. Chain: f. Fragment: extracellular domain.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Expression_system_cell: cho cells. Gene: apt1, fas, fas1, tnfrsf6. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.10Å
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R-factor:
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0.185
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R-free:
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0.221
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Authors:
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S.Zuger,C.Stirnimann,C.Briand,M.G.Grutter
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Key ref:
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M.Chodorge
et al.
(2012).
A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ,
19,
1187-1195.
PubMed id:
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Date:
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19-Aug-11
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Release date:
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09-May-12
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PROCHECK
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Headers
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References
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No UniProt id for this chain
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Cell Death Differ
19:1187-1195
(2012)
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PubMed id:
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A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
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M.Chodorge,
S.Züger,
C.Stirnimann,
C.Briand,
L.Jermutus,
M.G.Grütter,
R.R.Minter.
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ABSTRACT
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Links
