PDBsum entry 1ewo

Hydrolase/hydrolase inhibitor

PDB id: 1ewo

Contents

Protein chain

215 a.a. *

Ligands

VSC

Waters ×38

* Residue conservation analysis

PDB id:

1ewo

Name:

Hydrolase/hydrolase inhibitor

Title:

The cysteine protease cruzain bound to wrr-204

Structure:

Cruzain. Chain: a. Fragment: catalytic domain. Synonym: cruzipain, cruzaine. Engineered: yes

Source:

Trypanosoma cruzi. Organism_taxid: 5693. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.10Å R-factor: 0.221 R-free: 0.262

Authors:

L.S.Brinen,S.A.Gillmor,R.J.Fletterick

Key ref:

L.S.Brinen et al. Crystal structure of cruzain bound to wrr-204. To be published, .

Date:

26-Apr-00 Release date: 10-Jun-03

Protein chain

P25779  (CYSP_TRYCR) -  Cruzipain from Trypanosoma cruzi

Seq: 467 a.a.

Struc: 215 a.a.

Enzyme reactions

• Enzyme class: E.C.3.4.22.51 - cruzipain.