EC 3.4.22.51 - Cruzipain

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IntEnz Enzyme Nomenclature
EC 3.4.22.51

Names

Accepted name:
cruzipain
Other names:
congopain
cruzain
evansain
trypanopain
Systematic name:
-

Reaction

Comments:

In peptidase family C1. Is located in the digestive vacuoles of the parasitic trypanosome and contributes to the nutrition of the organism by digestion of host proteins.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Protein domains and families: PROSITE:PDOC00126
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Cazzulo, J.J., Stoka, V. and Turk, V.
    The major cysteine proteinase of Trypanosoma cruzi: a valid target for chemotherapy of Chagas disease.
    Curr. Pharm. Des. 7: 1143-1156 (2001). [PMID: 11472258]

[EC 3.4.23.51 created 2003]