EC 18.104.22.168 - Cruzipain
IntEnz Enzyme Nomenclature
- Broad endopeptidase specificity similar to that of cathepsin L.
In peptidase family C1. Is located in the digestive vacuoles of the parasitic trypanosome and contributes to the nutrition of the organism by digestion of host proteins.
Links to other databases
The major cysteine proteinase of Trypanosoma cruzi: a valid target for chemotherapy of Chagas disease.Curr. Pharm. Des. 7: 1143-1156 (2001). [PMID: 11472258]
[EC 22.214.171.124 created 2003]