_EC 4.1.3.40 chorismate lyase. 7 PDB entries  
EC 4.-.-.- Lyases. [10,261 PDB entries]
EC 4.1.-.- Carbon-carbon lyases. [2,336 PDB entries]
EC 4.1.3.- Oxo-acid-lyases. [233 PDB entries]
EC 4.1.3.40 chorismate lyase. [7 PDB entries]
1fw9

Reaction: chorismate = 4-hydroxybenzoate + pyruvate.
 


chorismate
 =
4-hydroxybenzoate
 +
pyruvate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Cl. Cpl.
Comments: Catalyzes the first step in the biosynthesis of ubiquinone in Escherichia coli and other Gram-negative bacteria. The yeast Saccharomyces cerevisiae can synthesize ubiquinone from either chorismate or tyrosine.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 7 PDB entries in enzyme class E.C.4.1.3.40

  PDB code Protein
1fw9
Chorismate lyase with bound product
Source: Escherichia coli. Organism_taxid: 562
Chain: A (164 residues) CATH domain: 3.40.1410.10
Bound ligand:   Het Group PHB corresponds to enzyme product 4-hydroxybenzoate
1g1b
Chorismate lyase (wild-type) with bound product
Source: Escherichia coli. Organism_taxid: 562
Chains: A, B (164 residues) CATH domain: 3.40.1410.10
Bound ligand:   Het Group PHB corresponds to enzyme product 4-hydroxybenzoate
1g81
Chorismate lyase with bound product, orthorhombic crystal form
Source: Escherichia coli. Organism_taxid: 562. Gene: ubic. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (164 residues) CATH domain: 3.40.1410.10
Bound ligand:   Het Group PHB corresponds to enzyme product 4-hydroxybenzoate
1jd3
Chorismate lyase g90a mutant with bound product
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (164 residues) CATH domain: 3.40.1410.10
Bound ligand:   Het Group PHB corresponds to enzyme product 4-hydroxybenzoate
1tt8
Chorismate lyase with product, 1.0 a resolution
Source: Escherichia coli. Organism_taxid: 562. Gene: ubic,b4039. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (164 residues) CATH domain: 3.40.1410.10
Bound ligand:   Het Group PHB corresponds to enzyme product 4-hydroxybenzoate
1xlr
Chorismate lyase with inhibitor vanillate
Source: Escherichia coli. Organism_taxid: 562. Gene: ubic. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (164 residues) CATH domain: 3.40.1410.10
Bound ligand:   Het Group VNL is 83.33% similar to enzyme product 4-hydroxybenzoate
2ahc
Chorismate lyase with inhibitor vanilate
Source: Escherichia coli. Organism_taxid: 562. Gene: ubic. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (164 residues) CATH domain: 3.40.1410.10
Bound ligand:   Het Group VNL is 83.33% similar to enzyme product 4-hydroxybenzoate