PDBsum entry 6vpp

Motor protein

PDB id: 6vpp

Contents

Protein chains

428 a.a.

421 a.a.

315 a.a.

Ligands

GTP

GDP

Metals

_MG

PDB id:

6vpp

Name:

Motor protein

Title:

Cryo-em structure of microtubule-bound klp61f motor with tail domain in the nucleotide-free state

Structure:

Tubulin alpha-1a chain. Chain: a. Synonym: alpha-tubulin 1,tubulin alpha-1 chain. Tubulin beta chain. Chain: b. Synonym: beta-tubulin. Kinesin-like protein klp61f. Chain: c. Synonym: bipolar kinesin krp-130.

Source:

Sus scrofa. Pig. Organism_taxid: 9823. Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: klp61f, klp2, cg9191. Expressed in: escherichia coli. Expression_system_taxid: 562

Authors:

T.Bodrug,E.M.Wilson-Kubalek,S.Nithianantham,G.Debs,C.V.Sindelar, R.Milligan,J.Al-Bassam

Key ref:

T.Bodrug et al. (2020). The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-Pa microtubule sliding.. Elife, 9, . PubMed id: 31958056

Date:

04-Feb-20 Release date: 19-Feb-20

Protein chain

P02550  (TBA1A_PIG) -  Tubulin alpha-1A chain from Sus scrofa

Seq: 451 a.a.

Struc: 428 a.a.

Protein chain

P02554  (TBB_PIG) -  Tubulin beta chain from Sus scrofa

Seq: 445 a.a.

Struc: 421 a.a.

Protein chain

P46863  (KL61_DROME) -  Kinesin-like protein Klp61F from Drosophila melanogaster

Seq: 1066 a.a.

Struc: 315 a.a.

Enzyme reactions

• Enzyme class 2: Chain A: E.C.3.6.5.- - ?????
• Enzyme class 3: Chains B, C: E.C.?

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.