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PDBsum entry 6fcc

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protein ligands links
Transferase PDB id
6fcc

 

 

 

 

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Contents
Protein chain
209 a.a.
Ligands
TLA
Waters ×147
PDB id:
6fcc
Name: Transferase
Title: Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt)
Structure: Atp phosphoribosyltransferase. Chain: a. Synonym: atp-prtase. Engineered: yes. Other_details: n- and c-terminal residues were disordered so do not appear in the coordinate sequence. The initial g remains after tev- cleavage of affinity tag.
Source: Psychrobacter arcticus (strain dsm 17307 / 273- 4). Organism_taxid: 259536. Strain: dsm 17307 / 273-4. Gene: hisg, psyc_1903. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c43.
Resolution:
1.89Å     R-factor:   0.209     R-free:   0.245
Authors: M.S.Alphey,Y.Ge,G.Fisher,C.M.Czekster,J.H.Naismith,R.G.Da Silva
Key ref: M.S.Alphey et al. Catalytic and anticatalytic snapshots of a short-Form phosphoribosyltransferase. Acs catalysis, .
Date:
20-Dec-17     Release date:   24-Oct-18    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q4FQF7  (HIS1_PSYA2) -  ATP phosphoribosyltransferase from Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4)
Seq:
Struc:
231 a.a.
209 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: E.C.2.4.2.17  - Atp phosphoribosyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Histidine Biosynthesis (early stages)
      Reaction: 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP
1-(5-phospho-beta-D-ribosyl)-ATP
+ diphosphate
= 5-phospho-alpha-D-ribose 1-diphosphate
+ ATP
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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