_EC 2.4.2.17 Atp phosphoribosyltransferase. 12 PDB entries  
EC 2.-.-.- Transferases. [17,806 PDB entries]
EC 2.4.-.- Glycosyltransferases. [1,911 PDB entries]
EC 2.4.2.- Pentosyltransferases. [903 PDB entries]
EC 2.4.2.17 Atp phosphoribosyltransferase. [12 PDB entries]    
1h3d

Pathway: Histidine Biosynthesis (early stages)
Reaction: 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = Atp + 5-phospho-alpha-D- ribose 1-diphosphate.
 

1-(5-phospho-beta-D-ribosyl)-ATP
+
diphosphate
=
ATP
+
5-phospho-alpha-D- ribose 1-diphosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Phosphoribosyl-ATP diphosphorylase. Phosphoribosyl-ATP pyrophosphorylase.
Comments: Involved in histidine biosynthesis.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 12 PDB entries in enzyme class E.C.2.4.2.17

  PDB code Protein
1h3d
Structure of the e.Coli atp-phosphoribosyltransferase
Source: Escherichia coli. Organism_taxid: 83333. Strain: k-12. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (288 residues) CATH domains: 3.40.190.10 3.40.190.10 3.30.70.120
Bound ligand:   Het Group AMP is 74.00% similar to enzyme product ATP
1nh7
Atp phosphoribosyltransferase (atp-prtase) from mycobacteriu tuberculosis
Source: Mycobacterium tuberculosis h37rv. Organism_taxid: 83332. Strain: h37rv. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (274 residues) CATH domains: 3.40.190.10 3.40.190.10 3.30.70.120
1nh8
Atp phosphoribosyltransferase (atp-prtase) from mycobacteriu tuberculosis in complex with amp and histidine
Source: Mycobacterium tuberculosis h37rv. Organism_taxid: 83332. Strain: h37rv. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (276 residues) CATH domains: 3.40.190.10 3.40.190.10 3.30.70.120
Bound ligand:   Het Group AMP is 74.19% similar to enzyme product ATP
1o63
Crystal structure of an atp phosphoribosyltransferase
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: hisg, tm1042. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (203 residues) CATH domains: 3.40.190.10 3.40.190.10
1o64
Crystal structure of an atp phosphoribosyltransferase
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: hisg, tm1042. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (203 residues) CATH domains: 3.40.190.10 3.40.190.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme reactant diphosphate
1q1k
Structure of atp-phosphoribosyltransferase from e. Coli comp pr-atp
Source: Escherichia coli. Organism_taxid: 562. Gene: hisg. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (288 residues) CATH domains: 3.40.190.10 3.40.190.10 3.30.70.120
Bound ligand:   Het Group PRT corresponds to enzyme reactant 1-(5-phospho-D-ribosyl)-ATP
1usy
Atp phosphoribosyl transferase (hisg:hisz) complex from thermotoga maritima
Source: Thermotoga maritima. Organism_taxid: 243274. Strain: msb8. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: E, F, G, H (202 residues) CATH domains: 3.40.190.10 3.40.190.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme reactant diphosphate
1ve4
Atp-phosphoribosyltransferase(hisg) from thermus thermophilu
Source: Thermus thermophilus. Organism_taxid: 274. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (201 residues) CATH domains: 3.40.190.10 3.40.190.10
1z7m
Atp phosphoribosyl transferase (hiszg atp-prtase) from lacto lactis
Source: Lactococcus lactis. Organism_taxid: 1358. Gene: hisz. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hisg.
Chains: F, G, H (201 residues) CATH domains: 3.40.190.10 3.40.190.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme reactant diphosphate
1z7n
Atp phosphoribosyl transferase (hiszg atp-prtase) from lactococcus lactis with bound prpp substrate
Source: Lactococcus lactis. Organism_taxid: 1358. Gene: hisz. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hisg.
Chains: E, G, H (203 residues) CATH domains: 3.40.190.10 3.40.190.10
Bound ligand:   Het Group PRP corresponds to enzyme product 5-phospho-alpha-D-ribose 1-diphosphate
2vd2
The crystal structure of hisg from b. Subtilis
Source: Bacillus subtilis. Organism_taxid: 1423. Strain: subtilis 168. Atcc: 23857. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (212 residues) CATH domains: 3.40.190.10 3.40.190.10
2vd3
The structure of histidine inhibited hisg from methanobacterium thermoautotrophicum
Source: Methanobacterium thermoautotrophicum. Organism_taxid: 187420. Strain: deltah. Atcc: 29183. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (289 residues) CATH domains: 3.40.190.10 3.40.190.10 3.30.70.120