PDBsum entry 4py3

Protein binding

PDB id: 4py3

Contents

Protein chains

(+ 4 more) 213 a.a.

Ligands

EDO ×2

Waters ×267

PDB id:

4py3

Name:

Protein binding

Title:

Crystal structure of the n-terminal fic domain of bep8 protein (virb- translocated bartonella effector protein) from bartonella sp. 1-1c

Structure:

Bartonella effector protein (bep) substrate of virb t4ss. Chain: a, b, c, d, e, f, g, h, i, j. Engineered: yes

Source:

Bartonella sp. 1-1c. Organism_taxid: 515256. Gene: b11c_110376. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.35Å R-factor: 0.243 R-free: 0.259

Authors:

Seattle Structural Genomics Center For Infectious Disease (Ssgcid)

Key ref:

D.M.Dranow et al. Crystal structure of the n-Terminal fic domain of bep protein (virb-Translocated bartonella effector protei bartonella sp. 1-1c. To be published, . PubMed id: 34442725

Date:

25-Mar-14 Release date: 10-Jun-15

Protein chains

E6YV77  (E6YV77_9HYPH) -  protein adenylyltransferase from Bartonella sp. 1-1C

Seq: 545 a.a.

Struc: 213 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.7.108 - protein adenylyltransferase.
• Reaction:
  1. L-seryl-[protein] + ATP = 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate
  2. L-threonyl-[protein] + ATP = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate
  3. L-tyrosyl-[protein] + ATP = O-(5'-adenylyl)-L-tyrosyl-[protein] + diphosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site