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PDBsum entry 4jz0
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PDB id:
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Hydrolase
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Title:
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X-ray structure of human glutamate carboxypeptidase ii (gcpii) in complex with ctt1055
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Structure:
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Glutamate carboxypeptidase 2. Chain: a. Fragment: unp residues 44-750. Synonym: cell growth-inhibiting gene 27 protein, folate hydrolase 1, folylpoly-gamma-glutamate carboxypeptidase, fgcp, glutamate carboxypeptidase ii, gcpii, membrane glutamate carboxypeptidase, mgcp, n-acetylated-alpha-linked acidic dipeptidase i, naaladase i, prostate-specific membrane antigen, psm, psma, pteroylpoly-gamma- glutamate carboxypeptidase.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: folh, folh1, gig27, naalad1, psm, psma. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Expression_system_cell: s2.
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Resolution:
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1.83Å
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R-factor:
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0.153
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R-free:
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0.171
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Authors:
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C.Barinka
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Key ref:
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T.Ganguly
et al.
A high affinity 18f-Labeled phosphoramidate peptidomi inhibitor as a psma-Targeted pet imaging agent for pr cancer.
To be published,
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Date:
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02-Apr-13
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Release date:
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02-Apr-14
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PROCHECK
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Headers
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References
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Q04609
(FOLH1_HUMAN) -
Glutamate carboxypeptidase 2 from Homo sapiens
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Seq:
Struc:
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750 a.a.
692 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.3.4.17.21
- glutamate carboxypeptidase Ii.
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Reaction:
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Release of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly-gamma-glutamates.
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Cofactor:
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Zn(2+)
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Links
