PDBsum entry 4gew

Hydrolase

PDB id: 4gew

Contents

Protein chain

324 a.a.

Ligands

GOL ×9

Waters ×137

PDB id:

4gew

Name:

Hydrolase

Title:

Crystal structure of tdp2 from c. Elegans

Structure:

5'-tyrosyl-DNA phosphodiesterase. Chain: a. Fragment: unp residues 1-362. Synonym: 5'-tyr-DNA phosphodiesterase. Engineered: yes

Source:

Caenorhabditis elegans. Nematode. Organism_taxid: 6239. Gene: y63d3a.4. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.35Å R-factor: 0.173 R-free: 0.207

Authors:

K.Shi,K.Kurahashi,H.Aihara

Key ref:

K.Shi et al. (2012). Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Nat Struct Biol, 19, 1372-1377. PubMed id: 23104058

Date:

02-Aug-12 Release date: 31-Oct-12

Protein chain

Q9XWG3  (TYDP2_CAEEL) -  5'-tyrosyl-DNA phosphodiesterase from Caenorhabditis elegans

Seq: 362 a.a.

Struc: 324 a.a.

Enzyme reactions

• Enzyme class: E.C.3.1.4.- - ?????

Nat Struct Biol 19:1372-1377 (2012)

PubMed id: 23104058

Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.

K.Shi, K.Kurahashi, R.Gao, S.E.Tsutakawa, J.A.Tainer, Y.Pommier, H.Aihara.

ABSTRACT

No abstract given.