PDBsum entry 4e4c

Hydrolase

PDB id: 4e4c

Contents

Protein chain

118 a.a.

Ligands

SO4 ×2

MES

Waters ×86

PDB id:

4e4c

Name:

Hydrolase

Title:

Crystal structure of notexin at 1.8 a resolution

Structure:

Phospholipase a2. Chain: a. Synonym: notexin, phosphatidylcholine 2-acylhydrolase. Ec: 3.1.1.4

Source:

Notechis scutatus scutatus. Mainland tiger snake. Organism_taxid: 70142

Resolution:

1.80Å R-factor: 0.266 R-free: 0.322

Authors:

A.Ullah,P.Spencer,M.T.Murakami,R.K.Arni

Key ref:

A.Ullah et al. High resolution structure of notexin. To be published, .

Date:

12-Mar-12 Release date: 28-Mar-12

Protein chain

P00608  (PA2B_NOTSC) -  Basic phospholipase A2 notexin from Notechis scutatus scutatus

Seq: 119 a.a.

Struc: 118 a.a.

Enzyme reactions

• Enzyme class: E.C.3.1.1.4 - phospholipase A2.
• Reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3- phosphocholine + a fatty acid + H⁺
• Cofactor: Ca(2+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site