 |
PDBsum entry 4b4c
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
|
|
|
|
|
|
|
|
|
|
Transcription
|
PDB id
|
|
|
|
4b4c
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PDB id:
|
 |
|
 |
| Name: |
 |
Transcription
|
 |
|
Title:
|
 |
Crystal structure of the DNA-binding domain of human chd1.
|
|
Structure:
|
 |
Chromodomain-helicase-DNA-binding protein 1. Chain: a. Fragment: DNA-binding domain, residues 1119-1327. Synonym: chd-1, chd1, atp-dependent helicase chd1. Engineered: yes
|
|
Source:
|
 |
Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-prare2.
|
|
Resolution:
|
 |
|
1.62Å
|
R-factor:
|
0.194
|
R-free:
|
0.226
|
|
|
Authors:
|
 |
C.K.Allerston,C.D.O.Cooper,L.Shrestha,M.Vollmar,N.Burgess-Brown, W.W.Yue,E.P.Carpenter,C.H.Arrowsmith,A.Edwards,C.Bountra,F.Von Delft,O.Gileadi
|
|
Key ref:
|
 |
C.K.Allerston
et al.
Crystal structure of the DNA-Binding domain of human.
To be published,
.
|
 |
|
Date:
|
 |
|
30-Jul-12
|
Release date:
|
15-Aug-12
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
Headers
|
 |
|
|
References
|
|
|
|
|
|
|
O14646
(CHD1_HUMAN) -
Chromodomain-helicase-DNA-binding protein 1 from Homo sapiens
|
|
|
|
Seq: Struc:
|
 |
 |
 |
1710 a.a.
187 a.a.
|
|
|
|
|
|
|
|
|
 |
 |
|
|
Key: |
 |
PfamA domain |
 |
 |
 |
Secondary structure |
 |
 |
CATH domain |
 |
|
|
|
|
 |
|
|
 |
 |
 |
 |
Enzyme class:
|
 |
E.C.3.6.4.12
- Dna helicase.
|
|
 |
 |
 |
 |
 |
Reaction:
|
 |
ATP + H2O = ADP + phosphate + H+
|
 |
 |
 |
 |
 |
ATP
|
+
|
H2O
|
=
|
ADP
|
+
|
phosphate
|
+
|
H(+)
|
|
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
|
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
|
|
 |
');
}
}
 |