_EC 3.6.4.12 Dna helicase. 227 PDB entries  
EC 3.-.-.- Hydrolases. [21,057 PDB entries]
EC 3.6.-.- Acting on acid anhydrides. [2,183 PDB entries]
EC 3.6.4.- Acting on acid anhydrides; involved in cellular and subcellular m [843 PDB entries]
EC 3.6.4.12 Dna helicase. [227 PDB entries]    
1b79

Reaction: Atp + H(2)O = adp + phosphate.
 


ATP
+ H(2)O
=
ADP
+
phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: Dna helicases utilize the energy from atp hydrolysis to unwind double-stranded Dna. Some of them unwind duplex Dna with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind Dna in both directions (14,15). Some helicases unwind Dna as well as rna (4,9). May be identical with Ec 3.6.4.13 (RNA helicase).
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 227 PDB entries in enzyme class E.C.3.6.4.12

  PDB code Protein
1b79
N-terminal domain of DNA replication protein dnab
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (102 residues) CATH domain: 1.10.860.10
1bby
DNA-binding domain from human rap30, nmr, minimized average
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (69 residues) CATH domain: 1.10.10.10
1bdx
E. Coli DNA helicase ruva with bound DNA holliday junction, alpha carbons and phosphate atoms only
Source: Synthetic: yes. Escherichia coli bl21(de3). Organism_taxid: 469008. Strain: bl21. Variant: de3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: de3.
Chains: A, B, C, D (190 residues)
1bvs
Ruva complexed to a holliday junction.
Source: Mycobacterium leprae. Organism_taxid: 1769. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell_line: bl21(de3).
Chains: A, B, C, D, E, F, G, H (183 residues) CATH domains: 2.40.50.140 1.10.150.20 1.10.8.10
1c7y
E.Coli ruva-holliday junction complex
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic: yes
Chain: A (199 residues) CATH domains: 2.40.50.140 1.10.150.20 1.10.8.10
1cr0
Crystal structure of the helicase domain of the gene4 protein of bacteriophage t7
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (242 residues) CATH domain: 3.40.50.300
1cr1
Crystal structure of the helicase domain of the gene 4 protein of bacteriophage t7: complex with dttp
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (245 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group TTP is 76.00% similar to enzyme reactant ATP
1cr2
Crystal structure of the helicase domain of the gene 4 protein of bacteriophage t7: complex with datp
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (239 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group DTP is 96.00% similar to enzyme reactant ATP
1cr4
Crystal structure of the helicase domain of the gene 4 protein of bacteriophage t7: complex with dtdp
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (243 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group TYD is 73.00% similar to enzyme product ADP
1cuk
Escherichia coli ruva protein at ph 4.9 and room temperature
Source: Escherichia coli. Organism_taxid: 562. Strain: 12 bl21 (de3). Cell_line: bl21. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (190 residues) CATH domains: 2.40.50.140 1.10.150.20 1.10.8.10
1d8l
E. Coli holliday junction binding protein ruva nh2 region lacking domain iii
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (140 residues) CATH domains: 1.10.150.20 2.40.50.140
1e0j
Gp4d helicase from phage t7 adpnp complex
Source: Phage t7. Organism_taxid: 10760. Gene: gene 4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (287 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ANP is 81.00% similar to enzyme product ADP
1e0k
Gp4d helicase from phage t7
Source: Phage t7. Organism_taxid: 10760. Gene: gene 4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (288 residues) CATH domain: 3.40.50.300
1f08
Crystal structure of the DNA-binding domain of the replication initiation protein e1 from papillomavirus
Source: Bovine papillomavirus. Organism_taxid: 10571. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (148 residues) CATH domain: 3.40.1310.10
1f3u
Crystal structure of the rap30/74 interaction domains of human tfiif
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, C, E, G (118 residues) CATH domain: Unassigned
1gku
Reverse gyrase from archaeoglobus fulgidus
Source: Archaeoglobus fulgidus. Organism_taxid: 224325. Strain: vc-16. Atcc: 49558. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: german collection of microorganisms (dsmz)
Chain: B (1011 residues) CATH domains: 2.20.20.30 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
1gl9
Archaeoglobus fulgidus reverse gyrase complexed with adpnp
Source: Archaeoglobus fulgidus. Organism_taxid: 224325. Strain: vc-16. Atcc: 49558. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: german collection of microorganisms (dsmz)
Chains: B, C (1020 residues) CATH domains: 2.20.20.30 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
Bound ligand:   Het Group ANP is 81.00% similar to enzyme product ADP
1hjp
Holliday junction binding protein ruva from e. Coli
Source: Escherichia coli. Organism_taxid: 562. Cell_line: bl21. Gene: ruva. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (186 residues) CATH domains: 2.40.50.140 1.10.150.20 1.10.8.10
1hqc
Structure of ruvb from thermus thermophilus hb8
Source: Thermus thermophilus. Organism_taxid: 274. Gene: ruvb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (314 residues) CATH domains: 3.40.50.300 1.10.8.60 1.10.10.10
1in4
Thermotoga maritima ruvb holliday junction branch migration motor
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: ruvb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (298 residues) CATH domains: 3.40.50.300 1.10.10.10 1.10.8.60
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
1in5
Thermogota maritima ruvb a156s mutant
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: ruvb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (301 residues) CATH domains: 3.40.50.300 1.10.10.10 1.10.8.60
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
1in6
Thermotoga maritima ruvb k64r mutant
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: ruvb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (300 residues) CATH domains: 3.40.50.300 1.10.10.10 1.10.8.60
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
1in7
Thermotoga maritima ruvb r170a
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: ruvb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (298 residues) CATH domains: 3.40.50.300 1.10.10.10 1.10.8.60
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
1in8
Thermotoga maritima ruvb t158v
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: ruvb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (298 residues) CATH domains: 3.40.50.300 1.10.10.10 1.10.8.60
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
1ixr
Ruva-ruvb complex
Source: Thermus thermophilus. Organism_taxid: 274. Gene: ruva. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ruvb.
Chains: A, B, C (135 residues) CATH domains: 2.40.50.140 1.10.150.20
Bound ligand:   Het Group ANP is 81.00% similar to enzyme product ADP
1ixs
Structure of ruvb complexed with ruva domain iii
Source: Thermus thermophilus. Organism_taxid: 274. Gene: ruva. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ruvb.
Chains: A, B (50 residues) CATH domain: 1.10.8.10
Bound ligand:   Het Group ANP is 81.00% similar to enzyme product ADP
1j7k
Thermotoga maritima ruvb p216g mutant
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: ruvb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (299 residues) CATH domains: 3.40.50.300 1.10.10.10 1.10.8.60
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
1jwe
Nmr structure of the n-terminal domain of e. Coli dnab helicase
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (114 residues) CATH domain: 1.10.860.10
1ka8
Crystal structure of the phage p4 origin-binding domain
Source: Enterobacteria phage p4. Organism_taxid: 10680. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (100 residues) CATH domain: 1.10.10.10
1ksx
Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex
Source: Synthetic: yes. Bovine papillomavirus. Organism_taxid: 10571. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, E, F, I, J, M, N (145 residues) CATH domain: 3.40.1310.10
1ksy
Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex
Source: Synthetic: yes. Bovine papillomavirus. Organism_taxid: 10571. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C (145 residues) CATH domain: 3.40.1310.10
1lvo
Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha- helical domain
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1mbm
Nsp4 proteinase from equine arteritis virus
Source: Equine arteritis virus. Organism_taxid: 11047. Gene: nsp4. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (198 residues) CATH domains: 2.40.10.10 2.40.10.10 3.30.40.20
1mi8
2.0 angstrom crystal structure of a dnab intein from synecho pcc 6803
Source: Synechocystis sp.. Organism_taxid: 1148. Strain: pcc 6803. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (141 residues) CATH domain: 2.170.16.10
1mm2
Solution structure of the 2nd phd domain from mi2b
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (61 residues) CATH domain: 3.30.40.10
1mm3
Solution structure of the 2nd phd domain from mi2b with c- terminal loop replaced by corresponding loop from wstf
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (61 residues) CATH domain: 3.30.40.10
1msz
Solution structure of the r3h domain from human smubp-2
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: smubp-2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (62 residues) CATH domain: 3.30.1370.50
1nui
Crystal structure of the primase fragment of bacteriophage t helicase protein
Source: Enterobacteria phage t7. Organism_taxid: 10760. Gene: 4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (242 residues) CATH domain: 2.20.25.10
1oyw
Structure of the recq catalytic core
Source: Escherichia coli. Organism_taxid: 562. Gene: recq. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (516 residues) CATH domains: 3.40.50.300 3.40.50.300 1.10.10.10
1oyy
Structure of the recq catalytic core bound to atp-gamma-s
Source: Escherichia coli. Organism_taxid: 562. Gene: recq. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (512 residues) CATH domains: 3.40.50.300 3.40.50.300 1.10.10.10
Bound ligand:   Het Group AGS is 93.00% similar to enzyme reactant ATP
1p4d
F factor trai relaxase domain
Source: Escherichia coli. Organism_taxid: 562. Gene: trai. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C (275 residues) CATH domains: Unassigned Unassigned
1p9u
Coronavirus main proteinase (3clpro) structure: basis for de anti-sars drugs
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: substrate-analog
Chains: A, B, C, D, E, F (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1pjr
Structure of DNA helicase
Source: Geobacillus stearothermophilus. Organism_taxid: 1422. Strain: nca1503. Gene: pcra. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (623 residues) CATH domains: 3.40.50.300 1.10.10.160 3.40.50.300 1.10.486.10
1q57
The crystal structure of the bifunctional primase-helicase o bacteriophage t7
Source: Enterobacteria phage t7. Organism_taxid: 10760. Gene: 4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F, G (483 residues) CATH domains: Unassigned 3.40.50.300
1qhg
Structure of DNA helicase mutant with adpnp
Source: Geobacillus stearothermophilus. Organism_taxid: 1422. Strain: nca1503. Gene: pcra. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (622 residues) CATH domains: 3.40.50.300 1.10.10.160 3.40.50.300 1.10.486.10
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
1qhh
Structure of DNA helicase with adpnp
Source: Geobacillus stearothermophilus. Organism_taxid: 1422. Strain: nca1503. Gene: pcra. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (164 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
1r9w
Crystal structure of the DNA-binding domain of the human papillomavirus type 18 (hpv-18) replication initiation protein e1
Source: Human papillomavirus type 18. Organism_taxid: 333761. Gene: e1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (138 residues) CATH domain: 3.40.1310.10
1rif
Crystal structure of the uvsw helicase from bacteriophage t4
Source: Enterobacteria phage t4. Organism_taxid: 10665. Gene: uvsw, dar. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (282 residues) CATH domains: Unassigned 3.40.50.300
1s9h
Crystal structure of adeno-associated virus type 2 rep40
Source: Adeno-associated virus - 2. Organism_taxid: 10804. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (268 residues) CATH domains: Unassigned 3.40.50.300
1tue
The x-ray structure of the papillomavirus helicase in complex with its molecular matchmaker e2
Source: Human papillomavirus type 18. Organism_taxid: 333761. Gene: e1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: e2.
Chains: A, D, F, H, K, M (201 residues) CATH domain: 3.40.50.300
1u0j
Crystal structure of aav2 rep40-adp complex
Source: Adeno-associated virus - 2. Organism_taxid: 10804. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domains: Unassigned Unassigned
1uaa
E. Coli rep helicase/DNA complex
Source: Escherichia coli. Organism_taxid: 562. Synthetic: yes
Chains: A, B (636 residues) CATH domains: 3.40.50.300 1.10.10.160 3.40.50.300 1.10.486.10
1uw7
Nsp9 protein from sars-coronavirus.
Source: Sars coronavirus hku-39849. Organism_taxid: 228404. Cell_line: vero e6. Expressed in: e. Coli.
Chain: A (122 residues) CATH domain: 2.40.10.250
1wud
E. Coli recq hrdc domain
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, D (77 residues) CATH domain: 1.10.150.80
2a0i
F factor trai relaxase domain bound to f orit single-strande
Source: Synthetic: yes. Other_details: synthesized oligonucleotide. Escherichia coli. Organism_taxid: 562. Gene: trai. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (293 residues)
2acf
Nmr structure of sars-cov non-structural protein nsp3a (sars sars coronavirus
Source: Sars coronavirus tor2. Organism_taxid: 227984. Strain: tor-2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (172 residues) CATH domain: 3.40.220.10
2ahm
Crystal structure of sars-cov super complex of non-structura proteins: the hexadecamer
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (77 residues) CATH domain: Unassigned
2axl
Solution structure of a multifunctional DNA- and protein- binding domain of human werner syndrome protein
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (144 residues) CATH domain: 1.10.10.10
2b2t
Tandem chromodomains of human chd1 complexed with histone h3 tail containing trimethyllysine 4 and phosphothreonine 3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in homo sapiens (humans).
Chains: A, B, C (176 residues) CATH domains: 2.40.50.40 2.40.50.40
Bound ligand:   Het Group TPO is 45.00% similar to enzyme product phosphate
2b2u
Tandem chromodomains of human chd1 complexed with histone h3 containing trimethyllysine 4 and dimethylarginine 2
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in homo sapie (humans).
Chains: A, B, C (173 residues) CATH domains: 2.40.50.40 2.40.50.40
2b2v
Crystal structure analysis of human chd1 chromodomains 1 and to histone h3 resi 1-15 mek4
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in homo sapie (humans).
Chains: A, B, C (175 residues) CATH domains: 2.40.50.40 2.40.50.40
2b2w
Tandem chromodomains of human chd1 complexed with histone h3 tail containing trimethyllysine 4
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in homo sapiens (humans).
Chains: A, B, C (177 residues) CATH domains: 2.40.50.40 2.40.50.40
2b2y
Tandem chromodomains of human chd1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C (175 residues) CATH domains: 2.40.50.40 2.40.50.40
2bby
DNA-binding domain from human rap30, nmr, 30 structures
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (69 residues) CATH domain: 1.10.10.10
2c3s
Structure of sars cov main proteinase at 1.9 a (ph6.5)
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sin2774. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (302 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2c9o
3d structure of the human ruvb-like helicase ruvbl1
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: de3.
Chains: A, B, C (398 residues) CATH domains: 3.40.50.300 Unassigned 1.10.8.60
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2cka
Solution structures of the brk domains of the human chromo helicase domain 7 and 8, reveals structural similarity with gyf domain suggesting a role in protein interaction
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta. Other_details: self made cdna library of multiple human carcinoma cell lines
Chain: A (58 residues) CATH domain: Unassigned
2ckc
Solution structures of the brk domains of the human chromo helicase domain 7 and 8, reveals structural similarity with gyf domain suggesting a role in protein interaction
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: self made cdna library of multiple human carcinoma cell lines
Chain: A (60 residues) CATH domain: Unassigned
2cqa
Solution structure of rsgi ruh-039, a fragment of c- terminal domain of ruvb-like 2 from human cdna
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl2, tip48, tip49b. Other_details: cell-free protein synthesis
Chain: A (95 residues)
2dgz
Solution structure of the helicase and rnase d c-terminal domain in werner syndrome atp-dependent helicase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wrn. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
Chain: A (113 residues) CATH domain: 1.10.150.80
2dl6
Solution structure of the first brk domain from human chromodomain-helicase-DNA-binding protein 8
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd8, kiaa1564. Expressed in: cell free synthesis. Other_details: cell free protein synthesis
Chain: A (83 residues) CATH domain: Unassigned
2e1e
Crystal structure of the hrdc domain of human werner syndrom wrn
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (94 residues) CATH domain: 1.10.150.80
2e1f
Crystal structure of the hrdc domain of human werner syndrom wrn
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (94 residues) CATH domain: 1.10.150.80
2e6l
Structure of mouse wrn exonuclease domain
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: wrn. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (186 residues) CATH domain: 3.30.420.10
2e6m
Structure of mouse werner exonuclease domain
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: wrn. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (186 residues) CATH domain: 3.30.420.10
2ee1
Solution structures of the chromo domain of human chromodomain helicase-DNA-binding protein 4
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd4. Other_details: cell-free protein synthesis
Chain: A (64 residues) CATH domain: 2.40.50.40
2epb
Solution structure of chromo domain 2 in chromodomain- helicase-DNA-binding protein 6
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd6. Other_details: cell-free protein synthesis
Chain: A (68 residues) CATH domain: 2.40.50.40
2fbt
Wrn exonuclease
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wrn, recq3, recql2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (196 residues) CATH domain: 3.30.420.10
2fbv
Wrn exonuclease, mn complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wrn, recq3, recql2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (194 residues) CATH domain: 3.30.420.10
2fbx
Wrn exonuclease, mg complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wrn, recq3, recql2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (195 residues) CATH domain: 3.30.420.10
2fby
Wrn exonuclease, eu complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wrn, recq3, recql2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (196 residues) CATH domain: 3.30.420.10
2fc0
Wrn exonuclease, mn dgmp complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wrn, recq3, recql2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (196 residues) CATH domain: 3.30.420.10
Bound ligand:   Het Group DGP is 78.57% similar to enzyme product ADP
2gdt
Nmr structure of the nonstructural protein 1 (nsp1) from the sars coronavirus
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (116 residues) CATH domain: Unassigned
2gri
Nmr structure of the sars-cov non-structural protein nsp3a
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (112 residues) CATH domain: Unassigned
2gx4
Crystal structure of sars coronavirus 3cl protease inhibitor
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2gxa
Crystal structure of papillomavirus e1 hexameric helicase with ssdna and mgadp
Source: Synthetic: yes. Bovine papillomavirus type 1. Organism_taxid: 10559. Strain: bpv-1. Gene: e1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (270 residues) CATH domains: Unassigned 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2h5x
Ruva from mycobacterium tuberculosis
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: ruva. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B, C, D (183 residues) CATH domains: 2.40.50.140 1.10.150.20 1.10.8.10
2h85
Crystal structure of nsp 15 from sars
Source: Sars coronavirus. Organism_taxid: 227859. Strain: frankfurt-1. Gene: nsp15. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (347 residues) CATH domains: Unassigned Unassigned Unassigned
2hsx
Nmr structure of the nonstructural protein 1 (nsp1) from the sars coronavirus
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (116 residues) CATH domain: Unassigned
2idy
Nmr structure of the sars-cov non-structural protein nsp3a
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (112 residues) CATH domain: Unassigned
2is1
Crystal structure of uvrd-DNA-so4 complex
Source: Synthetic: yes. Escherichia coli. Organism_taxid: 562. Gene: uvrd. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (649 residues) CATH domains: 3.40.50.300 1.10.10.160 3.40.50.300 1.10.486.10
2is2
Crystal structure of uvrd-DNA binary complex
Source: Synthetic: yes. Escherichia coli. Organism_taxid: 562. Gene: uvrd. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (642 residues) CATH domains: 3.40.50.300 1.10.10.160 3.40.50.300 1.10.486.10
2is4
Crystal structure of uvrd-DNA-adpnp ternary complex
Source: Synthetic: yes. Escherichia coli. Organism_taxid: 562. Gene: uvrd. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (646 residues) CATH domains: 3.40.50.300 1.10.10.160 3.40.50.300 1.10.486.10
Bound ligand:   Het Group ANP is 81.00% similar to enzyme product ADP
2is6
Crystal structure of uvrd-DNA-adpmgf3 ternary complex
Source: Synthetic: yes. Escherichia coli. Organism_taxid: 562. Gene: uvrd. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (654 residues) CATH domains: 3.40.50.300 1.10.10.160 3.40.50.300 1.10.486.10
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2j97
Human coronavirus 229e non structural protein 9 (nsp9)
Source: Human coronavirus 229e. Hcov 229e. Organism_taxid: 11137. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (98 residues) CATH domain: 2.40.10.250
2j98
Human coronavirus 229e non structural protein 9 cys69ala mutant (nsp9)
Source: Human coronavirus 229e. Hcov 229e. Organism_taxid: 11137. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B (106 residues) CATH domain: 2.40.10.250
2jm1
Structures and chemical shift assignments for the add domain atrx protein
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (141 residues) CATH domain: Unassigned
2jpn
Solution structure of t4 bacteriophage helicase uvsw.1
Source: Enterobacteria phage t4. Organism_taxid: 10665. Gene: uvsw, dar. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (79 residues) CATH domain: Unassigned
2jzd
Nmr structure of the domain 527-651 of the sars-cov nonstructural protein nsp3
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (129 residues) CATH domain: Unassigned
2jze
Nmr structure of the domain 527-651 of the sars-cov nonstructural protein nsp3, single conformer closest to the mean coordinates of an ensemble of twenty energy minimized conformers
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (129 residues) CATH domain: Unassigned
2jzf
Nmr conformer closest to the mean coordinates of the domain the sars-cov nonstructural protein nsp3
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (143 residues)
2k87
Nmr structure of a putative RNA binding protein (sars1) from coronavirus
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (116 residues)
2klq
The solution structure of cbd of human mcm6
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (114 residues)
2kmu
Recql4 amino-terminal domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: recql4, recq4. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (56 residues) CATH domain: Unassigned
2kv2
Solution structure of the human blm hrdc domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: blm. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (85 residues) CATH domain: 1.10.150.80
2l5u
Structure of the first phd finger (phd1) from chd4 (mi2b)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd4. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: pgex-6pe is an edited version of pgex-2t whi contains an hrv3c protease cleavage site.
Chain: A (61 residues) CATH domain: 3.30.40.10
2l75
Solution structure of chd4-phd2 in complex with h3k9me3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd4. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: a modified version of pgex-2t containing a h protease cleavage site.. Synthetic: yes.
Chain: A (56 residues) CATH domain: 3.30.40.10
2l8b
Trai (381-569)
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: ecok12f104, trai. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (189 residues) CATH domain: Unassigned
2l8k
Nmr structure of the arterivirus nonstructural protein 7 alp alpha)
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: bucyrus. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (123 residues) CATH domain: Unassigned
2lbm
Solution structure of the add domain of atrx complexed with tail h3 1-15 k9me3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic peptide
Chain: A (142 residues) CATH domain: Unassigned
2ld1
Structures and chemical shift assignments for the add domain atrx protein
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (142 residues) CATH domain: Unassigned
2le8
The protein complex for DNA replication
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm6. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cdt1.
Chain: A (114 residues) CATH domain: Unassigned
2lrr
Solution structure of the r3h domain from human smubp-2 in c with 2'-deoxyguanosine-5'-monophosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ighmbp2, smbp2, smubp-2, smubp2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (70 residues) CATH domain: 3.30.1370.50
2oca
The crystal structure of t4 uvsw
Source: Enterobacteria phage t4. Organism_taxid: 10665. Gene: uvsw, dar. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (494 residues) CATH domains: Unassigned 3.40.50.300
2ozk
Structure of an n-terminal truncated form of nendou (nsp15) from sars-coronavirus
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor-2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (306 residues) CATH domains: Unassigned Unassigned Unassigned
2pjr
Helicase product complex
Source: Synthetic: yes. Geobacillus stearothermophilus. Organism_taxid: 1422. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B, F, G (542 residues) CATH domains: 3.40.50.300 1.10.10.160 3.40.50.300 1.10.486.10
Bound ligand:   Het Group DG is 64.00% similar to enzyme product ADP
2pwx
Crystal structure of g11a mutant of sars-cov 3c-like proteas
Source: Sars coronavirus. Organism_taxid: 228407. Strain: bj01. Gene: rep. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (289 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2q6d
Crystal structure of infectious bronchitis virus (ibv) main protease
Source: Infectious bronchitis virus. Organism_taxid: 11120. Strain: m41. Gene: m41 3c-like protease gene. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B, C (296 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2q6f
Crystal structure of infectious bronchitis virus (ibv) main protease in complex with a michael acceptor inhibitor n3
Source: Infectious bronchitis virus. Organism_taxid: 11120. Strain: m41. Gene: m41 3c-like protease gene. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (294 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2q6g
Crystal structure of sars-cov main protease h41a mutant in c with an n-terminal substrate
Source: Sars coronavirus. Organism_taxid: 228407. Strain: bj01. Gene: rep. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Other_details: chemically synthesized.
Chains: A, B (305 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2q7t
Crystal structure of the f plasmid trai relaxase domain with the scissile thymidine base
Source: Escherichia coli. Gene: trai. Expressed in: escherichia coli.
Chains: A, B (267 residues) CATH domains: Unassigned Unassigned
Bound ligand:   Het Group TMP is 56.00% similar to enzyme product ADP
2q7u
Crystal structure of the f plasmid trai relaxase domain with the scissile thymidine base and imidodiphosphate
Source: Escherichia coli. Strain: trai. Gene: trai. Expressed in: escherichia coli.
Chains: A, B (268 residues) CATH domains: Unassigned Unassigned
Bound ligands:   Het Group TMP is 56.00% similar to enzyme product ADP
  Het Group PON is 66.00% similar to enzyme product phosphate
2qc2
Crystal structure of severe acute respiratory syndrome (sars protease asn214ala mutant
Source: Sars coronavirus. Virus. Gene: rep. Expressed in: escherichia coli.
Chains: A, B (305 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2qcy
Crystal structure of a monomeric form of severe acute respiratory syndrome (sars) 3c-like protease mutant
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2qiq
Structure-based design and synthesis and biological evaluation of peptidomimetic sars-3clpro inhibitors
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2r5u
Crystal structure of the n-terminal domain of dnab helicase mycobacterium tuberculosis
Source: Mycobacterium tuberculosis. Strain: h37rv. Gene: dnab. Expressed in: escherichia coli.
Chains: A, B, C, D, E, F (144 residues) CATH domain: Unassigned
2rhb
Crystal structure of nsp15-h234a mutant- hexamer in asymmetric unit
Source: Sars coronavirus. Organism_taxid: 227859. Strain: urbani isolate of sars-cov. Gene: nsp15. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell_line: bl21 star.
Chains: A, B, C, D, E, F (345 residues) CATH domains: Unassigned Unassigned Unassigned
2rnk
Nmr structure of the domain 513-651 of the sars-cov nonstructural protein nsp3
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (143 residues) CATH domain: Unassigned
2rrd
Structure of hrdc domain from human bloom syndrome protein,
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: blm, recq2, recql3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (101 residues) CATH domain: 1.10.150.80
2v0e
Brk domain from human chd7
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (55 residues) CATH domain: Unassigned
2v0f
Brk domain from human chd7
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (87 residues) CATH domain: Unassigned
2v1x
Crystal structure of human recq-like DNA helicase
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-prare2.
Chains: A, B (527 residues) CATH domains: 3.40.50.300 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2v6n
Crystal structures of the sars-coronavirus main proteinase inactivated by benzotriazole compounds
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2v9p
Crystal structure of papillomavirus e1 hexameric helicase DNA-free form
Source: Bovine papillomavirus type 1. Organism_taxid: 10559. Strain: bpv-1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (272 residues) CATH domains: Unassigned 3.40.50.300
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2vl6
Structural analysis of the sulfolobus solfataricus mcm protein n-terminal domain
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Atcc: 35092. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta.
Chains: A, B, C (259 residues) CATH domains: 3.30.1640.10 2.40.50.140
2vl7
Structure of s. Tokodaii xpd4
Source: Sulfolobus tokodaii. Organism_taxid: 111955. Strain: 7. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (459 residues) CATH domain: 3.40.50.300
2vsf
Structure of xpd from thermoplasma acidophilum
Source: Thermoplasma acidophilum. Organism_taxid: 2303. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (588 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned
2wwy
Structure of human recq-like helicase in complex with a DNA substrate
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-prare2. Synthetic: yes. Synthetic: yes
Chains: A, B (530 residues) CATH domains: 3.40.50.300 3.40.50.300
2xsz
The dodecameric human ruvbl1:ruvbl2 complex with truncated domains ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B, C, D, E, F (318 residues) CATH domains: 3.40.50.300 1.10.8.60
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
2xyq
Crystal structure of the nsp16 nsp10 sars coronavirus comple
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (287 residues) CATH domain: Unassigned
2xyr
Crystal structure of the nsp16 nsp10 sars coronavirus comple
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (286 residues) CATH domain: Unassigned
Bound ligand:   Het Group SFG is 50.00% similar to enzyme product ADP
2xyv
Crystal structure of the nsp16 nsp10 sars coronavirus comple
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (285 residues) CATH domain: Unassigned
Bound ligand:   Het Group SAH is 51.43% similar to enzyme product ADP
2yrn
Solution structure of the ch domain from human neuron navigator 2
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: nav2. Other_details: cell-free protein synthesis
Chain: A (129 residues) CATH domain: 1.10.418.10
2yy4
Crystal structure of ms8104
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: cell-free protein synthesis.
Chains: A, B (310 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z3c
A mechanistic view of enzyme inhibition and peptide hydrolys active site of the sars-cov 3c-like peptidase
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z3d
A mechanistic view of enzyme inhibition and peptide hydrolys active site of the sars-cov 3c-like peptidase
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z3e
A mechanistic view of enzyme inhibition and peptide hydrolys active site of the sars-cov 3c-like peptidase
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z94
Complex structure of sars-cov 3c-like protease with tdt
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z9g
Complex structure of sars-cov 3c-like protease with pma
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z9j
Complex structure of sars-cov 3c-like protease with epdtc
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (302 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z9k
Complex structure of sars-cov 3c-like protease with jmf1600
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (305 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z9l
Complex structure of sars-cov 3c-like protease with jmf1586
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2zj2
Archaeal DNA helicase hjm apo state in form 1
Source: Pyrococcus furiosus. Organism_taxid: 2261. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (653 residues) CATH domain: 3.40.50.300
2zj5
Archaeal DNA helicase hjm complexed with adp in form 1
Source: Pyrococcus furiosus. Organism_taxid: 2261. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (680 residues) CATH domains: 3.40.50.300 Unassigned Unassigned 1.10.150.20
2zj8
Archaeal DNA helicase hjm apo state in form 2
Source: Pyrococcus furiosus. Organism_taxid: 2261. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (700 residues) CATH domains: 3.40.50.300 Unassigned Unassigned 1.10.150.20
2zja
Archaeal DNA helicase hjm complexed with amppcp in form 2
Source: Pyrococcus furiosus. Organism_taxid: 2261. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (700 residues) CATH domains: 3.40.50.300 Unassigned Unassigned 1.10.150.20
2ztc
Mtruva form ii
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: ruva. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (188 residues) CATH domains: 2.40.50.140 1.10.150.20 1.10.8.10
2ztd
Mtruva form iii
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: ruva. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (189 residues) CATH domains: 2.40.50.140 1.10.150.20 1.10.8.10
2zte
Mtruva form iv
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: ruva. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (133 residues) CATH domains: 2.40.50.140 1.10.150.20
3aaf
Structure of wrn rqc domain bound to double-stranded DNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (109 residues) CATH domain: 1.10.10.10
3crv
"Xpd_helicase"
Source: Sulfolobus acidocaldarius. Gene: saci_0192. Expressed in: escherichia coli.
Chain: A (551 residues) CATH domains: Unassigned Unassigned Unassigned
3crw
"Xpd_apo"
Source: Sulfolobus acidocaldarius. Gene: saci_0192. Expressed in: escherichia coli.
Chain: 1 (485 residues) CATH domains: Unassigned Unassigned Unassigned
3d62
Development of broad-spectrum halomethyl ketone inhibitors a coronavirus main protease 3clpro
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3e1s
Structure of an n-terminal truncation of deinococcus radiodu
Source: Deinococcus radiodurans. Organism_taxid: 1299. Gene: recd. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (517 residues) CATH domains: Unassigned Unassigned 3.40.50.300
3e9s
A new class of papain-like protease/deubiquitinase inhibitors blocks sars virus replication
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (317 residues) CATH domains: Unassigned Unassigned Unassigned
3ebn
A special dimerization of sars-cov main proteasE C-terminal domain due to domain-swapping
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (100 residues) CATH domain: 1.10.1840.10
3ejf
Crystal structure of ibv x-domain at ph 8.5
Source: Avian infectious bronchitis virus (strain beaudette). Ibv. Organism_taxid: 11120. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (166 residues) CATH domain: 3.40.220.10
3ejg
Crystal structure of hcov-229e x-domain
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (165 residues) CATH domain: 3.40.220.10
3eke
Crystal structure of ibv x-domain at ph 5.6
Source: Avian infectious bronchitis virus (strain beaudette). Ibv. Organism_taxid: 11122. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (171 residues) CATH domain: 3.40.220.10
3eti
Structure of a cubic crystal form of x (adrp) domain from fcov
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H (168 residues) CATH domain: 3.40.220.10
3ew5
Structure of the tetragonal crystal form of x (adrp) domain from fcov
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C (168 residues) CATH domain: 3.40.220.10
Bound ligand:   Het Group 1GP is 50.00% similar to enzyme product phosphate
3f9v
Crystal structure of a near full-length archaeal mcm: functi insights for an aaa+ hexameric helicase
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Strain: p2. Gene: mcm, sso0774. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (595 residues)
3fld
Crystal structure of the trai c-terminal domain
Source: Escherichia coli k-12. Organism_taxid: 83333. Strain: k12. Gene: ecok12f104, trai. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (152 residues) CATH domains: Unassigned Unassigned
3gp8
Crystal structure of the binary complex of recd2 with DNA
Source: Deinococcus radiodurans r1. Organism_taxid: 243230. Strain: r1 / dsm 20539 / ifo 15346 / lmg 4051 / ncib 9279. Atcc: 13939. Gene: dr_1902, recd. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic DNA
Chain: A (551 residues) CATH domains: Unassigned Unassigned 3.40.50.300
3gpl
Crystal structure of the ternary complex of recd2 with DNA and adpnp
Source: Deinococcus radiodurans r1. Organism_taxid: 243230. Strain: r1 / dsm 20539 / ifo 15346 / lmg 4051 / ncib 9279. Atcc: 13939. Gene: dr_1902, recd2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic DNA
Chains: A, B (516 residues) CATH domains: Unassigned Unassigned 3.40.50.300
3gxv
Three-dimensional structure of n-terminal domain of dnab helicase from helicobacter pylori and its interactions with primase
Source: Helicobacter pylori. Organism_taxid: 210. Gene: hp_1362. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (122 residues)
3gzf
Structure of thE C-terminal domain of nsp4 from feline coron
Source: Feline coronavirus. Organism_taxid: 12663. Strain: fipv wsu-79. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E (96 residues)
3jzt
Structure of a cubic crystal form of x (adrp) domain from fcov with adp-ribose
Source: Feline coronavirus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (168 residues) CATH domain: 3.40.220.10
Bound ligand:   Het Group APR is 75.00% similar to enzyme product ADP
3lfu
Crystal structure of e. Coli uvrd
Source: Escherichia coli. Organism_taxid: 562. Gene: b3813, jw3786, mutu, pdeb, rad, recl, uvrd. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (633 residues) CATH domains: 3.40.50.300 1.10.10.160 3.40.50.300 1.10.486.10
3p4x
Helicase domain of reverse gyrase from thermotoga maritima
Source: Thermotoga maritima. Organism_taxid: 2336. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (399 residues) CATH domains: 3.40.50.300 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
3p4y
Helicase domain of reverse gyrase from thermotoga maritima -
Source: Thermotoga maritima. Organism_taxid: 2336. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (407 residues) CATH domains: 3.40.50.300 3.40.50.300
3pfi
2.7 angstrom resolution crystal structure of a probable holl junction DNA helicase (ruvb) from campylobacter jejuni subs nctc 11168 in complex with adenosine-5'-diphosphate
Source: Campylobacter jejuni subsp. Jejuni. Organism_taxid: 192222. Strain: nctc 11168. Gene: cjj8425_1444, ruvb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (301 residues) CATH domains: 3.40.50.300 1.10.8.60 1.10.10.10
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
3pjr
Helicase substrate complex
Source: Synthetic: yes. Geobacillus stearothermophilus. Organism_taxid: 1422. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (646 residues) CATH domains: 3.40.50.300 1.10.10.160 3.40.50.300 1.10.486.10
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
3q90
Crystal structure of the ntf2 domain of ras gtpase-activatin binding protein 1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp, g3bp1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (121 residues) CATH domain: 3.10.450.50
3ql9
Monoclinic complex structure of atrx add bound to histone h3 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans
Chain: A (125 residues) CATH domain: Unassigned
3qla
Hexagonal complex structure of atrx add bound to h3k9me3 pep
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans
Chains: A, D (127 residues) CATH domain: Unassigned
3qlc
Complex structure of atrx add domain bound to unmodified h3 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans
Chains: A, B (127 residues) CATH domain: Unassigned
3qln
Crystal structure of atrx add domain in free state
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (123 residues) CATH domain: Unassigned
3r24
Crystal structure of nsp10/nsp16 complex of sars coronavirus possible
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: 1a.
Chains: A, B (292 residues) CATH domain: Unassigned
Bound ligand:   Het Group SAM is 50.00% similar to enzyme product ADP
3u44
Crystal structure of addab-DNA complex
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: adda, bsu10630. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: addb, bsu10620. Synthetic: yes
Chains: A, B (1122 residues) CATH domains: 3.40.50.300 Unassigned Unassigned Unassigned 1.10.486.10
3u4q
Structure of addab-DNA complex at 2.8 angstroms
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: adda, bsu10630. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: addb, bsu10620. Synthetic: yes
Chains: A, B (1122 residues) CATH domains: 3.40.50.300 Unassigned Unassigned Unassigned 1.10.486.10
3ub0
Crystal structure of the nonstructural protein 7 and 8 compl feline coronavirus
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (190 residues) CATH domains: Unassigned Unassigned
3uk6
Crystal structure of the tip48 (tip49b) hexamer
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cgi-46, ino80j, ruvbl2, tip48, tip49b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (298 residues) CATH domains: 3.40.50.300 1.10.8.60
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
3upu
Crystal structure of the t4 phage sf1b helicase dda
Source: Enterobacteria phage t4. Organism_taxid: 10665. Gene: dda, sud. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B, C (439 residues) CATH domains: Unassigned Unassigned Unassigned
3v62
Structure of the s. Cerevisiae srs2 c-terminal domain in com pcna conjugated to sumo on lysine 164
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: w3031a. Gene: d9719.15, smt3, ydr510w. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: pol30, ybr0811, ybr088c. Gene: hpr5, j0913, radh, srs2, yjl092w.
Chains: C, F (21 residues)
3vc8
Crystal structure of thE C-terminal cytoplasmic domain of no structural protein 4 from mouse hepatitis virus a59
Source: Murine hepatitis virus. Organism_taxid: 591071. Strain: a59. Gene: murine hepatitis virus strain a59 orf1ab, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (81 residues) CATH domain: Unassigned
3vcb
C425s mutant of thE C-terminal cytoplasmic domain of non-str protein 4 from mouse hepatitis virus a59
Source: Murine hepatitis virus. Organism_taxid: 591071. Strain: a59. Gene: murine hepatitis virus strain a59 orf1ab, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (89 residues) CATH domain: Unassigned
3we2
Structure of blm rqc domain bound to a phosphate ion
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: blm. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (121 residues) CATH domain: 1.10.10.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
3we3
Structure of blm rqc domain bound to an arsenate ion
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: blm. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (121 residues) CATH domain: 1.10.10.10
4a15
Crystal structure of an xpd DNA complex
Source: Thermoplasma acidophilum. Organism_taxid: 2303. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: ril. Synthetic: yes
Chain: A (596 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned
4a1f
Crystal structure of c-terminal domain of helicobacter pylori dnab helicase
Source: Helicobacter pylori. Organism_taxid: 210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (323 residues) CATH domain: 3.40.50.300
4b3f
Crystal structure of 1ghmbp2 helicase
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: X (625 residues) CATH domains: Unassigned Unassigned Unassigned
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
4b3g
Crystal structure of ighmbp2 helicase in complex with RNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta. Synthetic: yes
Chains: A, B (614 residues) CATH domains: Unassigned Unassigned Unassigned
4b4c
Crystal structure of the DNA-binding domain of human chd1.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-prare2.
Chain: A (187 residues) CATH domains: Unassigned Unassigned
4bk0
Crystal structure of the kix domain of human recql5 (domain- swapped dimer)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: ril.
Chains: A, B (92 residues) CATH domains: Unassigned Unassigned
4cdg
Crystal structure of the bloom's syndrome helicase blm in complex with nanobody
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Lama glama. Llama. Organism_taxid: 9844. Cell: b-lymphocyte.
Chains: A, B (625 residues) CATH domains: 3.40.50.300 3.40.50.300 1.10.10.10 1.10.150.80
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
4ceh
Crystal structure of addab with a forked DNA substrate
Source: Bacillus subtilis subsp. Subtilis str. Organism_taxid: 224308. Atcc: 23857. Expressed in: escherichia coli b. Expression_system_taxid: 37762. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Other_details: synthetic construct
Chains: A, B (1154 residues) CATH domains: 3.40.50.300 Unassigned Unassigned Unassigned 1.10.486.10
4cei
Crystal structure of adpnp-bound addab with a forked DNA sub
Source: Bacillus subtilis subsp. Subtilis str. Organism_taxid: 224308. Atcc: 23857. Expressed in: escherichia coli b. Expression_system_taxid: 37762. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B (1170 residues) CATH domains: 3.40.50.300 Unassigned Unassigned Unassigned 1.10.486.10
Bound ligand:   Het Group ANP is 81.25% similar to enzyme product ADP
4cej
Crystal structure of addab-DNA-adpnp complex at 3 angstrom r
Source: Bacillus subtilis subsp. Subtilis str. Organism_taxid: 224308. Atcc: 23857. Expressed in: escherichia coli b. Expression_system_taxid: 37762. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B (1177 residues) CATH domains: 3.40.50.300 Unassigned Unassigned Unassigned 1.10.486.10
Bound ligand:   Het Group ANP is 81.25% similar to enzyme product ADP
4cgz
Crystal structure of the bloom's syndrome helicase blm in co with DNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Organism_taxid: 32630
Chain: A (629 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
4ddt
Thermotoga maritima reverse gyrase, c2 form 2
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: rgy, topr, tm_0173. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (1102 residues) CATH domains: Unassigned 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
4ddu
Thermotoga maritima reverse gyrase, c2 form 1
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: rgy, topr, tm_0173. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (1102 residues) CATH domains: Unassigned 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
4ddv
Thermotoga maritima reverse gyrase, triclinic form
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: rgy, topr, tm_0173. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (1102 residues) CATH domains: Unassigned 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
4ddw
Thermotoga maritima reverse gyrase, c-centered orthorhombic
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: rgy, topr, tm_0173. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (1102 residues) CATH domains: Unassigned 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
Bound ligand:   Het Group POP is 55.56% similar to enzyme product phosphate
4ddx
Thermotoga maritima reverse gyrase, primitive monoclinic for
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: rgy, topr, tm_0173. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (1102 residues)
4ern
Crystal structure of thE C-terminal domain of human xpb/ercc excision repair protein at 1.80 a
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ercc3, xpb, xpbc. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (229 residues) CATH domain: Unassigned
4fcj
Crystal structure of the ntf2-like domain of human g3bp1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (128 residues) CATH domain: 3.10.450.50
4fcm
Crystal structure of the ntf2-like domain of human g3bp1 in with a peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (132 residues) CATH domain: 3.10.450.50
4fdg
Crystal structure of an archaeal mcm filament
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Strain: p2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: B, A, C, D, E (592 residues)
4iia
Low resolution crystal structure of the ntf2-like domain of g3bp1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (131 residues) CATH domain: 3.10.450.50
4ium
Equine arteritis virus papain-like protease 2 (plp2) covalen to ubiquitin
Source: Equine arteritis virus. Eav. Organism_taxid: 11047. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
Chain: A (127 residues) CATH domain: Unassigned
4m6b
Crystal structure of yeast swr1-z domain in complex with h2a dimer
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: htb1, h2b1, spt12, ydr224c, yd9934.09c, htz1, h2az, h yol012c, o2345. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: swr1, ydr334w, d9651.6.
Chains: C, F (23 residues)
4n0n
Crystal structure of arterivirus nonstructural protein 10 (h
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: equine arteritis virus. Gene: 1a-1b, nsp10, rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (401 residues)
4n0o
Complex structure of arterivirus nonstructural protein 10 (h with DNA
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: equine arteritis virus. Gene: 1a-1b, nsp10, rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, C, E, G (395 residues)
4nw2
Tandem chromodomains of human chd1 in complex with influenza c-terminal tail trimethylated at k229
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Influenza a virus. Organism_taxid: 1348507
Chains: A, C (173 residues) CATH domains: 2.40.50.40 2.40.50.40
4o3m
Ternary complex of bloom's syndrome helicase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: blm, recq2, recql3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: chemically synthesised oligonucleotide.. Other_details: chemically synthesised oligonucleotide.
Chain: A (613 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
4o42
Tandem chromodomains of human chd1 in complex with influenza terminal tail dimethylated at k229
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chd1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Influenza a virus. Organism_taxid: 387159.
Chain: A (173 residues) CATH domains: 2.40.50.40 2.40.50.40